Format

Send to:

Choose Destination
    • Showing Current items.

    GSTA1 glutathione S-transferase alpha 1 [ Bos taurus (cattle) ]

    Gene ID: 777644, updated on 18-Apr-2019

    Summary

    Gene symbol
    GSTA1
    Gene description
    glutathione S-transferase alpha 1
    See related
    Ensembl:ENSBTAG00000021516
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs

    Genomic context

    See GSTA1 in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 23 NC_037350.1 (25122366..25137232, complement)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 23 AC_000180.1 (24875605..24890466, complement)

    Chromosome 23 - NC_037350.1Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase alpha 2 Neighboring gene glutathione S-transferase A1-like Neighboring gene uncharacterized LOC112443730 Neighboring gene glutathione S-transferase alpha 5 Neighboring gene glutathione S-transferase, alpha 3

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Homology

    Clone Names

    • MGC127978

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    glutathione transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    steroid delta-isomerase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    glutathione derivative biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    glutathione metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    prostaglandin metabolic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    glutathione S-transferase A1
    Names
    GST class-alpha member 1
    NP_001071617.1
    XP_024839527.1
    XP_024839528.1
    XP_024839529.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001078149.1NP_001071617.1  glutathione S-transferase A1

      See identical proteins and their annotated locations for NP_001071617.1

      Status: PROVISIONAL

      Source sequence(s)
      BC102540
      UniProtKB/Swiss-Prot
      Q28035
      Related
      ENSBTAP00000005618.5, ENSBTAT00000005618.6
      Conserved Domains (3) summary
      PTZ00057
      Location:1198
      PTZ00057; glutathione s-transferase; Provisional
      cd03208
      Location:86220
      GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases
      cd03077
      Location:482
      GST_N_Alpha; GST_N family, Class Alpha subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, ...

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037350.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      25122366..25137232 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024983759.1XP_024839527.1  glutathione S-transferase A1 isoform X1

      Conserved Domains (2) summary
      cd03208
      Location:36170
      GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases
      cl00388
      Location:132
      Thioredoxin_like; Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
    2. XM_024983761.1XP_024839529.1  glutathione S-transferase A1 isoform X2

      Conserved Domains (1) summary
      cd03208
      Location:1127
      GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases
    3. XM_024983760.1XP_024839528.1  glutathione S-transferase A1 isoform X2

      Conserved Domains (1) summary
      cd03208
      Location:1127
      GST_C_Alpha; C-terminal, alpha helical domain of Class Alpha Glutathione S-transferases
    Support Center