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    Shq1 SHQ1 homolog (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 72171, updated on 31-Jan-2019

    Summary

    Official Symbol
    Shq1provided by MGI
    Official Full Name
    SHQ1 homolog (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1919421
    See related
    Ensembl:ENSMUSG00000035378
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Grim-1; 2810403P18Rik
    Expression
    Ubiquitous expression in liver E14 (RPKM 2.7), CNS E11.5 (RPKM 2.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Shq1 in Genome Data Viewer
    Location:
    6; 6 D3
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (100571811..100671175, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (100523076..100621151, complement)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700049E22 gene Neighboring gene predicted gene, 33741 Neighboring gene ubiquitin-conjugating enzyme E2 variant 2 pseudogene Neighboring gene glucoside xylosyltransferase 2 Neighboring gene high mobility group box 3 pseudogene Neighboring gene protein phosphatase 4, regulatory subunit 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    box H/ACA snoRNP assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of rRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    ribonucleoprotein complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_181590.5NP_853621.2  protein SHQ1 homolog

      See identical proteins and their annotated locations for NP_853621.2

      Status: VALIDATED

      Source sequence(s)
      AC162389, AK012978, BY776788, CB522035, CF746515
      Consensus CDS
      CCDS39580.2
      UniProtKB/Swiss-Prot
      Q7TMX5
      Related
      ENSMUSP00000127797.1, ENSMUST00000170667.7
      Conserved Domains (3) summary
      cd00298
      Location:978
      ACD_sHsps_p23-like; This domain family includes the alpha-crystallin domain (ACD) of alpha-crystallin-type small heat shock proteins (sHsps) and a similar domain found in p23-like proteins. sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, ...
      pfam04925
      Location:245414
      SHQ1; SHQ1 protein
      cl21457
      Location:179266
      TIM_phosphate_binding; TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      100571811..100671175 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006506669.3XP_006506732.1  protein SHQ1 homolog isoform X2

      UniProtKB/Swiss-Prot
      Q7TMX5
      Related
      ENSMUSP00000086656.6, ENSMUST00000089245.6
      Conserved Domains (2) summary
      cd00298
      Location:978
      ACD_sHsps_p23-like; This domain family includes the alpha-crystallin domain (ACD) of alpha-crystallin-type small heat shock proteins (sHsps) and a similar domain found in p23-like proteins. sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, ...
      pfam04925
      Location:244303
      SHQ1; SHQ1 protein
    2. XM_006506668.3XP_006506731.1  protein SHQ1 homolog isoform X1

      Conserved Domains (3) summary
      cd00298
      Location:978
      ACD_sHsps_p23-like; This domain family includes the alpha-crystallin domain (ACD) of alpha-crystallin-type small heat shock proteins (sHsps) and a similar domain found in p23-like proteins. sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, ...
      pfam04925
      Location:245405
      SHQ1; SHQ1 protein
      cl21457
      Location:179266
      TIM_phosphate_binding; TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate ...
    3. XM_006506670.3XP_006506733.1  protein SHQ1 homolog isoform X3

      Conserved Domains (3) summary
      cd00298
      Location:978
      ACD_sHsps_p23-like; This domain family includes the alpha-crystallin domain (ACD) of alpha-crystallin-type small heat shock proteins (sHsps) and a similar domain found in p23-like proteins. sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, ...
      pfam04925
      Location:245358
      SHQ1; SHQ1 protein
      cl21457
      Location:179266
      TIM_phosphate_binding; TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate ...
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