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    CASP4 caspase 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 704864, updated on 29-Apr-2017

    Summary

    Gene symbol
    CASP4
    Gene description
    caspase 4
    See related
    Ensembl:ENSMMUG00000009850
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs

    Genomic context

    See CASP4 in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    102 current Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (97818055..97844062, complement)
    Build 1.2 previous assembly Mmul_051212 (GCF_000002255.3) 14 NC_007871.1 (103518790..103544847, complement)

    Chromosome 14 - NC_027906.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106993453 Neighboring gene caspase 12 Neighboring gene caspase 5 Neighboring gene caspase 1

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • NOD-like receptor signaling pathway, organism-specific biosystem (from KEGG)
      NOD-like receptor signaling pathway, organism-specific biosystemSpecific families of pattern recognition receptors are responsible for detecting various pathogens and generating innate immune responses. The intracellular NOD-like receptor (NLR) family contains mo...
    • NOD-like receptor signaling pathway, conserved biosystem (from KEGG)
      NOD-like receptor signaling pathway, conserved biosystemSpecific families of pattern recognition receptors are responsible for detecting various pathogens and generating innate immune responses. The intracellular NOD-like receptor (NLR) family contains mo...

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    caspase-4
    Names
    caspase 4, apoptosis-related cysteine peptidase
    caspase-4 isoform alpha
    NP_001247885.1
    XP_014971016.1
    XP_014971017.1
    XP_014971018.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001260956.1NP_001247885.1  caspase-4

      See identical proteins and their annotated locations for NP_001247885.1

      Status: PROVISIONAL

      Source sequence(s)
      JU473387
      UniProtKB/TrEMBL
      F7A0F5
      Related
      ENSMMUP00000012893.3, ENSMMUT00000013759.3
      Conserved Domains (2) summary
      smart00115
      Location:126375
      CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
      cd08325
      Location:586
      CARD_CASP1-like; Caspase activation and recruitment domain found in Caspase-1 and related proteins

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_8.0.1 Primary Assembly

    Genomic

    1. NC_027906.1 Reference Mmul_8.0.1 Primary Assembly

      Range
      97818055..97844062 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015115531.1XP_014971017.1  caspase-4 isoform X1

      Conserved Domains (2) summary
      smart00115
      Location:114363
      CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
      cd08325
      Location:174
      CARD_CASP1-like; Caspase activation and recruitment domain found in Caspase-1 and related proteins
    2. XM_015115532.1XP_014971018.1  caspase-4 isoform X1

      Conserved Domains (2) summary
      smart00115
      Location:114363
      CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
      cd08325
      Location:174
      CARD_CASP1-like; Caspase activation and recruitment domain found in Caspase-1 and related proteins
    3. XM_015115530.1XP_014971016.1  caspase-4 isoform X1

      Related
      ENSMMUP00000012894.3, ENSMMUT00000013760.3
      Conserved Domains (2) summary
      smart00115
      Location:114363
      CASc; Caspase, interleukin-1 beta converting enzyme (ICE) homologues
      cd08325
      Location:174
      CARD_CASP1-like; Caspase activation and recruitment domain found in Caspase-1 and related proteins
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