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    thbs1b thrombospondin 1b [ Danio rerio (zebrafish) ]

    Gene ID: 561901, updated on 14-Feb-2019

    Summary

    Official Symbol
    thbs1bprovided by ZNC
    Official Full Name
    thrombospondin 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-020708-1
    See related
    Ensembl:ENSDARG00000010785
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    Tsp-1; thbs1; wu:fc48c03; si:dkey-11e23.1
    Orthologs

    Genomic context

    See thbs1b in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (29037620..29051702, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (29134741..29148827, complement)
    103 previous assembly Zv9 (GCF_000002035.4) 20 NC_007131.5 (29063530..29077620, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene acyl-CoA thioesterase 21 Neighboring gene G protein-coupled receptor 176 Neighboring gene katanin p80 subunit B-like 1 Neighboring gene ER membrane protein complex subunit 7

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular matrix binding IEA
    Inferred from Electronic Annotation
    more info
     
    heparin binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    inflammatory response IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of angiogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of angiogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    collagen-containing extracellular matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular space IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    thrombospondin-1
    Names
    thrombospondin 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      29037620..29051702 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_685303.9XP_690395.4  thrombospondin-1 isoform X2

      UniProtKB/TrEMBL
      F1QEE7
      Related
      ENSDARP00000012255.8, ENSDART00000017090.10
      Conserved Domains (9) summary
      smart00209
      Location:495547
      TSP1; Thrombospondin type 1 repeats
      sd00001
      Location:763785
      TSP3; TSP3 repeat_short [structural motif]
      sd00002
      Location:787821
      TSP3; TSP3 repeat_long [structural motif]
      sd00003
      Location:691726
      TSP3_1C; TSP3 repeat_1C [structural motif]
      pfam00093
      Location:317371
      VWC; von Willebrand factor type C domain
      pfam02412
      Location:846882
      TSP_3; Thrombospondin type 3 repeat
      pfam05735
      Location:9721169
      TSP_C; Thrombospondin C-terminal region
      pfam12947
      Location:650689
      EGF_3; EGF domain
      cl22861
      Location:25220
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    2. XM_005160762.4XP_005160819.1  thrombospondin-1 isoform X1

      UniProtKB/TrEMBL
      F1QL35
      Related
      ENSDARP00000120705.2, ENSDART00000140350.3
      Conserved Domains (9) summary
      smart00209
      Location:496548
      TSP1; Thrombospondin type 1 repeats
      sd00001
      Location:764786
      TSP3; TSP3 repeat_short [structural motif]
      sd00002
      Location:788822
      TSP3; TSP3 repeat_long [structural motif]
      sd00003
      Location:692727
      TSP3_1C; TSP3 repeat_1C [structural motif]
      pfam00093
      Location:318372
      VWC; von Willebrand factor type C domain
      pfam02412
      Location:847883
      TSP_3; Thrombospondin type 3 repeat
      pfam05735
      Location:9731170
      TSP_C; Thrombospondin C-terminal region
      pfam12947
      Location:651690
      EGF_3; EGF domain
      cl22861
      Location:25220
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
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