Format

Send to:

Choose Destination
    • Showing Current items.

    parp1 poly (ADP-ribose) polymerase 1 [ Danio rerio (zebrafish) ]

    Gene ID: 560788, updated on 14-Feb-2019

    Summary

    Official Symbol
    parp1provided by ZNC
    Official Full Name
    poly (ADP-ribose) polymerase 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3955
    See related
    Ensembl:ENSDARG00000019529
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    wu:fc60f12; zgc:110092; si:dkey-206f10.3
    Orthologs

    Genomic context

    See parp1 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (43648438..43689779)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (43751360..43792701)
    103 previous assembly Zv9 (GCF_000002035.4) 20 NC_007131.5 (43680050..43721542)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110438195 Neighboring gene si:dkey-206f10.1 Neighboring gene Pim proto-oncogene, serine/threonine kinase, related 124 Neighboring gene adenosine receptor A1 pseudogene Neighboring gene lin-9 DREAM MuvB core complex component Neighboring gene Mix paired-like homeobox

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC110092

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    NAD binding IEA
    Inferred from Electronic Annotation
    more info
     
    NAD+ ADP-ribosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    NAD+ ADP-ribosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein ADP-ribosylase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring glycosyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    double-strand break repair IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein ADP-ribosylation IEA
    Inferred from Electronic Annotation
    more info
     
    protein poly-ADP-ribosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    poly [ADP-ribose] polymerase 1
    Names
    poly (ADP-ribose) polymerase family, member 1
    NP_001038407.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044942.1NP_001038407.1  poly [ADP-ribose] polymerase 1

      Status: PROVISIONAL

      Source sequence(s)
      BX470188
      UniProtKB/TrEMBL
      Q5RHR0
      Related
      ENSDARP00000008364.7, ENSDART00000017269.8
      Conserved Domains (6) summary
      cd08001
      Location:542644
      WGR_PARP1_like; WGR domain of poly(ADP-ribose) polymerase 1 and similar proteins
      PLN03123
      Location:71009
      PLN03123; poly [ADP-ribose] polymerase; Provisional
      cd01437
      Location:6611005
      parp_like; Poly(ADP-ribose) polymerase (parp) catalytic domain catalyses the covalent attachment of ADP-ribose units from NAD+ to itself and to a limited number of other DNA binding proteins, which decreases their affinity for DNA. Poly(ADP-ribose) polymerase is a ...
      pfam00533
      Location:385461
      BRCT; BRCA1 C Terminus (BRCT) domain
      pfam00645
      Location:1385
      zf-PARP; Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region
      pfam08063
      Location:274325
      PADR1; PADR1 (NUC008) domain

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      43648438..43689779
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center