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    map3k7 mitogen-activated protein kinase kinase kinase 7 [ Danio rerio (zebrafish) ]

    Gene ID: 553788, updated on 14-Feb-2019

    Summary

    Official Symbol
    map3k7provided by ZNC
    Official Full Name
    mitogen-activated protein kinase kinase kinase 7provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041001-135
    See related
    Ensembl:ENSDARG00000020469
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    zgc:110612; si:ch211-225h9.1
    Orthologs

    Genomic context

    See map3k7 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (24151003..24183449, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (24251904..24284430, complement)
    103 previous assembly Zv9 (GCF_000002035.4) 20 NC_007131.5 (24134567..24164860, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene BTB and CNC homology 1, basic leucine zipper transcription factor 2b Neighboring gene uncharacterized LOC101886561 Neighboring gene transfer RNA proline (anticodon UGG) Neighboring gene transfer RNA serine (anticodon UGA)

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Homology

    Clone Names

    • MGC110612

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    MAP kinase kinase kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    MAP kinase kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    magnesium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    JNK cascade IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    blood vessel morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of I-kappaB kinase/NF-kappaB signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mitogen-activated protein kinase kinase kinase 7
    Names
    TGF-beta-activated kinase TAK1
    tak1
    NP_001018586.1
    XP_009292938.1
    XP_009292939.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001020750.1NP_001018586.1  mitogen-activated protein kinase kinase kinase 7

      See identical proteins and their annotated locations for NP_001018586.1

      Status: PROVISIONAL

      Source sequence(s)
      BC095335
      UniProtKB/TrEMBL
      Q503G7
      Related
      ENSDARP00000006286.8, ENSDART00000025862.11
      Conserved Domains (2) summary
      smart00219
      Location:18266
      TyrKc; Tyrosine kinase, catalytic domain
      cd14058
      Location:24274
      STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      24151003..24183449 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009294664.3XP_009292939.1  mitogen-activated protein kinase kinase kinase 7 isoform X1

      See identical proteins and their annotated locations for XP_009292939.1

      UniProtKB/TrEMBL
      A0A0R4IVJ5
      Conserved Domains (2) summary
      smart00219
      Location:25273
      TyrKc; Tyrosine kinase, catalytic domain
      cd14058
      Location:31281
      STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1
    2. XM_009294663.3XP_009292938.1  mitogen-activated protein kinase kinase kinase 7 isoform X1

      See identical proteins and their annotated locations for XP_009292938.1

      UniProtKB/TrEMBL
      A0A0R4IVJ5
      Related
      ENSDARP00000138323.1, ENSDART00000171184.3
      Conserved Domains (2) summary
      smart00219
      Location:25273
      TyrKc; Tyrosine kinase, catalytic domain
      cd14058
      Location:31281
      STKc_TAK1; Catalytic domain of the Serine/Threonine Kinase, Transforming Growth Factor beta Activated Kinase-1
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