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    PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [ Bos taurus (cattle) ]

    Gene ID: 530001, updated on 14-Jan-2019

    Summary

    Official Symbol
    PIK3CGprovided by VGNC
    Official Full Name
    phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gammaprovided by VGNC
    Primary source
    VGNC:VGNC:32892
    See related
    BGD:BT26617; Ensembl:ENSBTAG00000020848
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs

    Genomic context

    See PIK3CG in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 4 NC_037331.1 (47988347..48028141)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 4 AC_000161.1 (48267525..48303221)

    Chromosome 4 - NC_037331.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104972036 Neighboring gene 60S ribosomal protein L31 pseudogene Neighboring gene coiled-coil domain containing 71 like Neighboring gene uncharacterized LOC112446374 Neighboring gene 39S ribosomal protein L22, mitochondrial pseudogene Neighboring gene uncharacterized LOC104972045

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC157122

    General protein information

    Preferred Names
    phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
    Names
    phosphoinositide-3-kinase, catalytic, gamma polypeptide
    NP_001095595.1
    XP_005205479.1
    XP_005205480.1
    XP_005205481.1
    XP_024846504.1
    XP_024846505.1
    XP_024846506.1
    XP_024846508.1
    XP_024846509.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001102125.2NP_001095595.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

      See identical proteins and their annotated locations for NP_001095595.1

      Status: PROVISIONAL

      Source sequence(s)
      BC149468
      UniProtKB/TrEMBL
      A6QPT0
      Related
      ENSBTAP00000027780.4, ENSBTAT00000027780.5
      Conserved Domains (4) summary
      cd08399
      Location:350527
      C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
      smart00144
      Location:203312
      PI3K_rbd; PI3-kinase family, Ras-binding domain
      cd00872
      Location:549725
      PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
      cl21453
      Location:729877
      PKc_like; Protein Kinases, catalytic domain

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037331.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      47988347..48028141
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005205424.4XP_005205481.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1

      See identical proteins and their annotated locations for XP_005205481.1

      Conserved Domains (4) summary
      cd08399
      Location:350527
      C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
      cd00872
      Location:549725
      PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
      cd00894
      Location:7291095
      PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
      pfam00794
      Location:203312
      PI3K_rbd; PI3-kinase family, ras-binding domain
    2. XM_024990740.1XP_024846508.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X2

      Conserved Domains (4) summary
      cd08399
      Location:350527
      C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
      cd00872
      Location:549725
      PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
      pfam00794
      Location:203312
      PI3K_rbd; PI3-kinase family, ras-binding domain
      cl21453
      Location:7291010
      PKc_like; Protein Kinases, catalytic domain
    3. XM_005205423.4XP_005205480.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1

      See identical proteins and their annotated locations for XP_005205480.1

      Conserved Domains (4) summary
      cd08399
      Location:350527
      C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
      cd00872
      Location:549725
      PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
      cd00894
      Location:7291095
      PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
      pfam00794
      Location:203312
      PI3K_rbd; PI3-kinase family, ras-binding domain
    4. XM_024990741.1XP_024846509.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X3

      Conserved Domains (4) summary
      cd08399
      Location:350527
      C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
      cd00872
      Location:549725
      PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
      pfam00794
      Location:203312
      PI3K_rbd; PI3-kinase family, ras-binding domain
      cl21453
      Location:729958
      PKc_like; Protein Kinases, catalytic domain
    5. XM_024990738.1XP_024846506.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1

      Conserved Domains (4) summary
      cd08399
      Location:350527
      C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
      cd00872
      Location:549725
      PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
      cd00894
      Location:7291095
      PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
      pfam00794
      Location:203312
      PI3K_rbd; PI3-kinase family, ras-binding domain
    6. XM_005205422.4XP_005205479.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1

      See identical proteins and their annotated locations for XP_005205479.1

      Related
      ENSBTAP00000064044.1, ENSBTAT00000080364.1
      Conserved Domains (4) summary
      cd08399
      Location:350527
      C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
      cd00872
      Location:549725
      PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
      cd00894
      Location:7291095
      PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
      pfam00794
      Location:203312
      PI3K_rbd; PI3-kinase family, ras-binding domain
    7. XM_024990736.1XP_024846504.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1

      Conserved Domains (4) summary
      cd08399
      Location:350527
      C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
      cd00872
      Location:549725
      PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
      cd00894
      Location:7291095
      PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
      pfam00794
      Location:203312
      PI3K_rbd; PI3-kinase family, ras-binding domain
    8. XM_024990737.1XP_024846505.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1

      Conserved Domains (4) summary
      cd08399
      Location:350527
      C2_PI3K_class_I_gamma; C2 domain present in class I gamma phosphatidylinositol 3-kinases (PI3Ks)
      cd00872
      Location:549725
      PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
      cd00894
      Location:7291095
      PI3Kc_IB_gamma; Catalytic domain of Class IB Phosphoinositide 3-kinase gamma
      pfam00794
      Location:203312
      PI3K_rbd; PI3-kinase family, ras-binding domain
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