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    BMI1 BMI1 proto-oncogene, polycomb ring finger [ Bos taurus (cattle) ]

    Gene ID: 510666, updated on 18-Feb-2019

    Summary

    Gene symbol
    BMI1
    Gene description
    BMI1 proto-oncogene, polycomb ring finger
    See related
    BGD:BT14753; Ensembl:ENSBTAG00000015584
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    PCGF4
    Orthologs

    Genomic context

    See BMI1 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 13 NC_037340.1 (23430480..23441040)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 13 AC_000170.1 (23709229..23713074)

    Chromosome 13 - NC_037340.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC112449266 Neighboring gene transfer RNA asparagine (anticodon GUU) Neighboring gene COMM domain containing 3 Neighboring gene sperm associated antigen 6 Neighboring gene transfer RNA opal suppressor (anticodon UCA) Neighboring gene uncharacterized LOC112449267

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC134151

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    promoter-specific chromatin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    histone H2A-K119 monoubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    negative regulation of gene expression, epigenetic ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of ubiquitin-protein transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    PcG protein complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    ubiquitin ligase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    polycomb complex protein BMI-1
    Names
    BMI1 polycomb ring finger oncogene
    polycomb group RING finger protein 4
    polycomb group ring finger 4

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001038072.1NP_001033161.1  polycomb complex protein BMI-1

      See identical proteins and their annotated locations for NP_001033161.1

      Status: PROVISIONAL

      Source sequence(s)
      BC109871
      UniProtKB/Swiss-Prot
      Q32KX7
      Conserved Domains (3) summary
      pfam16207
      Location:162226
      RAWUL; RAWUL domain RING finger- and WD40-associated ubiquitin-like
      cd16736
      Location:1265
      RING-HC_PCGF4; RING finger found in polycomb group RING finger protein 4 (PCGF4) and similar proteins
      cl28410
      Location:4168
      RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037340.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      23430480..23441040
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_025000489.1XP_024856257.1  polycomb complex protein BMI-1 isoform X2

      Related
      ENSBTAP00000058683.1, ENSBTAT00000068448.1
      Conserved Domains (3) summary
      pfam16207
      Location:162226
      RAWUL; RAWUL domain RING finger- and WD40-associated ubiquitin-like
      cd16736
      Location:1265
      RING-HC_PCGF4; RING finger found in polycomb group RING finger protein 4 (PCGF4) and similar proteins
      cl28410
      Location:4168
      RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
    2. XM_025000490.1XP_024856258.1  polycomb complex protein BMI-1 isoform X2

      Related
      ENSBTAP00000020705.4, ENSBTAT00000020705.5
      Conserved Domains (3) summary
      pfam16207
      Location:162226
      RAWUL; RAWUL domain RING finger- and WD40-associated ubiquitin-like
      cd16736
      Location:1265
      RING-HC_PCGF4; RING finger found in polycomb group RING finger protein 4 (PCGF4) and similar proteins
      cl28410
      Location:4168
      RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
    3. XM_025000492.1XP_024856260.1  polycomb complex protein BMI-1 isoform X2

      Conserved Domains (3) summary
      pfam16207
      Location:162226
      RAWUL; RAWUL domain RING finger- and WD40-associated ubiquitin-like
      cd16736
      Location:1265
      RING-HC_PCGF4; RING finger found in polycomb group RING finger protein 4 (PCGF4) and similar proteins
      cl28410
      Location:4168
      RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
    4. XM_025000488.1XP_024856256.1  polycomb complex protein BMI-1 isoform X1

      Conserved Domains (3) summary
      pfam16207
      Location:216280
      RAWUL; RAWUL domain RING finger- and WD40-associated ubiquitin-like
      cd16736
      Location:66119
      RING-HC_PCGF4; RING finger found in polycomb group RING finger protein 4 (PCGF4) and similar proteins
      cl28410
      Location:58222
      RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
    5. XM_025000491.1XP_024856259.1  polycomb complex protein BMI-1 isoform X2

      Related
      ENSBTAP00000066261.1, ENSBTAT00000073960.1
      Conserved Domains (3) summary
      pfam16207
      Location:162226
      RAWUL; RAWUL domain RING finger- and WD40-associated ubiquitin-like
      cd16736
      Location:1265
      RING-HC_PCGF4; RING finger found in polycomb group RING finger protein 4 (PCGF4) and similar proteins
      cl28410
      Location:4168
      RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
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