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    NCF4 neutrophil cytosolic factor 4 [ Bos taurus (cattle) ]

    Gene ID: 507859, updated on 20-Jan-2019

    Summary

    Official Symbol
    NCF4provided by VGNC
    Official Full Name
    neutrophil cytosolic factor 4provided by VGNC
    Primary source
    VGNC:VGNC:31913
    See related
    BGD:BT19103; Ensembl:ENSBTAG00000007531
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Orthologs

    Genomic context

    See NCF4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 5 NC_037332.1 (75265746..75284407)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 5 AC_000162.1 (75641116..75659776)

    Chromosome 5 - NC_037332.1Genomic Context describing neighboring genes Neighboring gene NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 Neighboring gene uncharacterized LOC101906435 Neighboring gene intraflagellar transport 27 Neighboring gene parvalbumin Neighboring gene colony stimulating factor 2 receptor beta common subunit Neighboring gene 60S ribosomal protein L7 pseudogene

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Homology

    Clone Names

    • MGC138034

    General protein information

    Preferred Names
    neutrophil cytosol factor 4
    Names
    neutrophil cytosolic factor 4, 40kDa

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045983.1NP_001039448.1  neutrophil cytosol factor 4

      See identical proteins and their annotated locations for NP_001039448.1

      Status: PROVISIONAL

      Source sequence(s)
      BC113230
      UniProtKB/TrEMBL
      Q2HJA6
      Related
      ENSBTAP00000072054.1, ENSBTAT00000084691.1
      Conserved Domains (3) summary
      cd06399
      Location:238328
      PB1_P40; The PB1 domain is essential part of the p40 adaptor protein which plays an important role in activating phagocyte NADPH oxidase during phagocytosis. The PB1 domain is a modular domain mediating specific protein-protein interaction which play a role in ...
      cd06882
      Location:19141
      PX_p40phox; The phosphoinositide binding Phox Homology domain of the p40phox subunit of NADPH oxidase
      cd11869
      Location:174227
      SH3_p40phox; Src Homology 3 domain of the p40phox subunit of NADPH oxidase

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037332.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      75265746..75284407
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024991520.1XP_024847288.1  neutrophil cytosol factor 4 isoform X2

      Conserved Domains (3) summary
      cd06882
      Location:19141
      PX_p40phox; The phosphoinositide binding Phox Homology domain of the p40phox subunit of NADPH oxidase
      cd11869
      Location:174227
      SH3_p40phox; Src Homology 3 domain of the p40phox subunit of NADPH oxidase
      cl02720
      Location:238259
      PB1; The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...
    2. XM_015471166.2XP_015326652.2  neutrophil cytosol factor 4 isoform X3

      Related
      ENSBTAP00000009911.5, ENSBTAT00000009911.5
      Conserved Domains (3) summary
      cd06882
      Location:19141
      PX_p40phox; The phosphoinositide binding Phox Homology domain of the p40phox subunit of NADPH oxidase
      cd11869
      Location:174227
      SH3_p40phox; Src Homology 3 domain of the p40phox subunit of NADPH oxidase
      cl02720
      Location:238256
      PB1; The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...
    3. XM_024991519.1XP_024847287.1  neutrophil cytosol factor 4 isoform X1

      Conserved Domains (3) summary
      cd06882
      Location:19141
      PX_p40phox; The phosphoinositide binding Phox Homology domain of the p40phox subunit of NADPH oxidase
      cd11869
      Location:174227
      SH3_p40phox; Src Homology 3 domain of the p40phox subunit of NADPH oxidase
      cl02720
      Location:238256
      PB1; The PB1 domain is a modular domain mediating specific protein-protein interactions which play a role in many critical cell processes, such as osteoclastogenesis, angiogenesis, early cardiovascular development, and cell polarity. A canonical PB1-PB1 ...
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