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    tab2 TGF-beta activated kinase 1 (MAP3K7) binding protein 2 [ Danio rerio (zebrafish) ]

    Gene ID: 494163, updated on 14-Feb-2019

    Summary

    Official Symbol
    tab2provided by ZNC
    Official Full Name
    TGF-beta activated kinase 1 (MAP3K7) binding protein 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-933
    See related
    Ensembl:ENSDARG00000021509
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    map3k7ip2; zgc:77446
    Orthologs

    Genomic context

    See tab2 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (1329508..1350296)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (1308522..1329345)
    103 previous assembly Zv9 (GCF_000002035.4) 20 NC_007131.5 (1352940..1373480)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene protein-L-isoaspartate (D-aspartate) O-methyltransferase Neighboring gene nucleoporin 43 Neighboring gene scavenger receptor class A, member 5 (putative) Neighboring gene metabolism of cobalamin associated C

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    chordate embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    convergent extension involved in gastrulation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heart development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 

    General protein information

    Preferred Names
    TGF-beta-activated kinase 1 and MAP3K7-binding protein 2
    Names
    TGF-beta-activated kinase 1-binding protein 2
    mitogen-activated protein kinase kinase kinase 7 interacting protein 2
    mitogen-activated protein kinase kinase kinase 7-interacting protein 2 homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001316693.1NP_001303622.1  TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

      Status: VALIDATED

      Source sequence(s)
      BC065982, CK126241, CR536610
      UniProtKB/Swiss-Prot
      Q5RFW2
      Related
      ENSDARP00000019647.4, ENSDART00000017791.7
      Conserved Domains (3) summary
      smart00547
      Location:685708
      ZnF_RBZ; Zinc finger domain
      cd14362
      Location:950
      CUE_TAB2_TAB3; CUE domain found in the N-terminal of TGF-beta-activated kinase 1 and MAP3K7-binding proteins TAB2, TAB3 and similar proteins
      sd00029
      Location:686705
      zf-RanBP2; RanBP2-type Zn finger [structural motif]

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      1329508..1350296
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017352472.2XP_017207961.1  TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform X1

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001009900.1: Suppressed sequence

      Description
      NM_001009900.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
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