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    MRE11 MRE11 homolog, double strand break repair nuclease [ Canis lupus familiaris (dog) ]

    Gene ID: 494006, updated on 26-Sep-2018

    Summary

    Official Symbol
    MRE11provided by VGNC
    Official Full Name
    MRE11 homolog, double strand break repair nucleaseprovided by VGNC
    Primary source
    VGNC:VGNC:43361
    See related
    Ensembl:ENSCAFG00000004162
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    MRE11A
    Orthologs

    Genomic context

    See MRE11 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 21 NC_006603.3 (6448909..6528185)

    Chromosome 21 - NC_006603.3Genomic Context describing neighboring genes Neighboring gene piwi like RNA-mediated gene silencing 4 Neighboring gene chromosome 21 C11orf97 homolog Neighboring gene fucosyltransferase 4 Neighboring gene ankyrin repeat domain 49 Neighboring gene G protein-coupled receptor 83 Neighboring gene IZUMO1 receptor, JUNO

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006603.3 Chromosome 21 Reference CanFam3.1 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Homology

    General protein information

    Preferred Names
    double-strand break repair protein MRE11
    Names
    MRE11 homolog A, double strand break repair nuclease
    MRE11 meiotic recombination 11 homolog A
    meiotic recombination 11-like protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006603.3 Reference CanFam3.1 Primary Assembly

      Range
      6448909..6528185
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005633354.2XP_005633411.1  double-strand break repair protein MRE11 isoform X1

      See identical proteins and their annotated locations for XP_005633411.1

      UniProtKB/TrEMBL
      F1PUK4
      Conserved Domains (3) summary
      TIGR00583
      Location:10402
      mre11; DNA repair protein (mre11)
      cd00840
      Location:14275
      MPP_Mre11_N; Mre11 nuclease, N-terminal metallophosphatase domain
      pfam04152
      Location:295461
      Mre11_DNA_bind; Mre11 DNA-binding presumed domain
    2. XM_005633352.2XP_005633409.1  double-strand break repair protein MRE11 isoform X1

      See identical proteins and their annotated locations for XP_005633409.1

      UniProtKB/TrEMBL
      F1PUK4
      Related
      ENSCAFP00000006193.3, ENSCAFT00000006688.4
      Conserved Domains (3) summary
      TIGR00583
      Location:10402
      mre11; DNA repair protein (mre11)
      cd00840
      Location:14275
      MPP_Mre11_N; Mre11 nuclease, N-terminal metallophosphatase domain
      pfam04152
      Location:295461
      Mre11_DNA_bind; Mre11 DNA-binding presumed domain
    3. XM_005633351.3XP_005633408.1  double-strand break repair protein MRE11 isoform X1

      See identical proteins and their annotated locations for XP_005633408.1

      UniProtKB/TrEMBL
      F1PUK4
      Conserved Domains (3) summary
      TIGR00583
      Location:10402
      mre11; DNA repair protein (mre11)
      cd00840
      Location:14275
      MPP_Mre11_N; Mre11 nuclease, N-terminal metallophosphatase domain
      pfam04152
      Location:295461
      Mre11_DNA_bind; Mre11 DNA-binding presumed domain
    4. XM_005633355.2XP_005633412.1  double-strand break repair protein MRE11 isoform X2

      Conserved Domains (2) summary
      cd00840
      Location:34192
      MPP_Mre11_N; Mre11 nuclease, N-terminal metallophosphatase domain
      pfam04152
      Location:212378
      Mre11_DNA_bind; Mre11 DNA-binding presumed domain
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