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    HDAC5 histone deacetylase 5 [ Canis lupus familiaris (dog) ]

    Gene ID: 490941, updated on 26-Sep-2018

    Summary

    Official Symbol
    HDAC5provided by VGNC
    Official Full Name
    histone deacetylase 5provided by VGNC
    Primary source
    VGNC:VGNC:49093
    See related
    Ensembl:ENSCAFG00000014334
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs

    Genomic context

    See HDAC5 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 9 NC_006591.3 (19261075..19297669)

    Chromosome 9 - NC_006591.3Genomic Context describing neighboring genes Neighboring gene ankyrin repeat and SOCS box containing 16 Neighboring gene chromosome 9 C17orf53 homolog Neighboring gene glucose-6-phosphatase catalytic subunit 3 Neighboring gene LSM12 homolog

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006591.3 Chromosome 9 Reference CanFam3.1 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Alcoholism, organism-specific biosystem (from KEGG)
      Alcoholism, organism-specific biosystemAlcoholism, also called dependence on alcohol (ethanol), is a chronic relapsing disorder that is progressive and has serious detrimental health outcomes. As one of the primary mediators of the reward...
    • Alcoholism, conserved biosystem (from KEGG)
      Alcoholism, conserved biosystemAlcoholism, also called dependence on alcohol (ethanol), is a chronic relapsing disorder that is progressive and has serious detrimental health outcomes. As one of the primary mediators of the reward...
    • Apelin signaling pathway, organism-specific biosystem (from KEGG)
      Apelin signaling pathway, organism-specific biosystemApelin is an endogenous peptide capable of binding the apelin receptor (APJ), which was originally described as an orphan G-protein-coupled receptor. Apelin and APJ are widely expressed in various ti...
    • Cell cycle, organism-specific biosystem (from WikiPathways)
      Cell cycle, organism-specific biosystem(From http://en.wikipedia.org/wiki/Cell_cycle) The cell cycle is the series of events that takes place in a cell leading to its division and duplication (replication). Regulation of the cell cycle in...
    • Epstein-Barr virus infection, organism-specific biosystem (from KEGG)
      Epstein-Barr virus infection, organism-specific biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • Epstein-Barr virus infection, conserved biosystem (from KEGG)
      Epstein-Barr virus infection, conserved biosystemEpstein-Barr virus (EBV) is a ubiquitous human herpesvirus that is associated with oncogenesis. EBV infection to primary human B lymphocytes leads to induction of EBV-specific HLA-restricted cytotoxi...
    • Viral carcinogenesis, organism-specific biosystem (from KEGG)
      Viral carcinogenesis, organism-specific biosystemThere is a strong association between viruses and the development of human malignancies. We now know that at least six human viruses, Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C vi...
    • Viral carcinogenesis, conserved biosystem (from KEGG)
      Viral carcinogenesis, conserved biosystemThere is a strong association between viruses and the development of human malignancies. We now know that at least six human viruses, Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C vi...

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    histone deacetylase 5
    XP_005624466.1
    XP_005624467.1
    XP_013971996.1
    XP_013971998.1
    XP_022278619.1
    XP_022278620.1
    XP_022278621.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006591.3 Reference CanFam3.1 Primary Assembly

      Range
      19261075..19297669
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014116523.2XP_013971998.1  histone deacetylase 5 isoform X4

      Conserved Domains (2) summary
      cd10007
      Location:6641080
      HDAC5; Histone deacetylase 5
      cl25407
      Location:59146
      ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)
    2. XM_022422912.1XP_022278620.1  histone deacetylase 5 isoform X5

      Conserved Domains (2) summary
      cd10007
      Location:6471063
      HDAC5; Histone deacetylase 5
      cl25407
      Location:42129
      ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)
    3. XM_005624409.3XP_005624466.1  histone deacetylase 5 isoform X2

      Conserved Domains (2) summary
      cd10007
      Location:6741090
      HDAC5; Histone deacetylase 5
      cl25407
      Location:69156
      ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)
    4. XM_022422913.1XP_022278621.1  histone deacetylase 5 isoform X5

      Related
      ENSCAFP00000042468.1, ENSCAFT00000042851.2
      Conserved Domains (2) summary
      cd10007
      Location:6471063
      HDAC5; Histone deacetylase 5
      cl25407
      Location:42129
      ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)
    5. XM_005624410.3XP_005624467.1  histone deacetylase 5 isoform X3

      Conserved Domains (2) summary
      cd10007
      Location:6731089
      HDAC5; Histone deacetylase 5
      cl25407
      Location:68155
      ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)
    6. XM_022422911.1XP_022278619.1  histone deacetylase 5 isoform X2

      Related
      ENSCAFP00000021172.4, ENSCAFT00000022795.4
      Conserved Domains (2) summary
      cd10007
      Location:6741090
      HDAC5; Histone deacetylase 5
      cl25407
      Location:69156
      ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)
    7. XM_014116521.2XP_013971996.1  histone deacetylase 5 isoform X1

      Conserved Domains (2) summary
      cd10007
      Location:6921108
      HDAC5; Histone deacetylase 5
      cl23765
      Location:87174
      iSH2_PI3K_IA_R; Inter-Src homology 2 (iSH2) helical domain of Class IA Phosphoinositide 3-kinase Regulatory subunits
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