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    EFNA1 ephrin A1 [ Canis lupus familiaris (dog) ]

    Gene ID: 490431, updated on 26-Sep-2018

    Summary

    Official Symbol
    EFNA1provided by VGNC
    Official Full Name
    ephrin A1provided by VGNC
    Primary source
    VGNC:VGNC:40226
    See related
    Ensembl:ENSCAFG00000017069
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs

    Genomic context

    See EFNA1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 7 NC_006589.3 (42373197..42381161, complement)

    Chromosome 7 - NC_006589.3Genomic Context describing neighboring genes Neighboring gene solute carrier family 50 member 1 Neighboring gene dolichyl-phosphate mannosyltransferase subunit 3 Neighboring gene ephrin A3 Neighboring gene ephrin A4

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006589.3 Chromosome 7 Reference CanFam3.1 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Axon guidance, organism-specific biosystem (from KEGG)
      Axon guidance, organism-specific biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
    • Axon guidance, conserved biosystem (from KEGG)
      Axon guidance, conserved biosystemAxon guidance represents a key stage in the formation of neuronal network. Axons are guided by a variety of guidance factors, such as netrins, ephrins, Slits, and semaphorins. These guidance cues are...
    • Axon guidance, organism-specific biosystem (from REACTOME)
      Axon guidance, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Developmental Biology, organism-specific biosystem (from REACTOME)
      Developmental Biology, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • EPH-Ephrin signaling, organism-specific biosystem (from REACTOME)
      EPH-Ephrin signaling, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • EPH-ephrin mediated repulsion of cells, organism-specific biosystem (from REACTOME)
      EPH-ephrin mediated repulsion of cells, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • EPHA-mediated growth cone collapse, organism-specific biosystem (from REACTOME)
      EPHA-mediated growth cone collapse, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • PI3K-Akt signaling pathway, organism-specific biosystem (from KEGG)
      PI3K-Akt signaling pathway, organism-specific biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
    • PI3K-Akt signaling pathway, conserved biosystem (from KEGG)
      PI3K-Akt signaling pathway, conserved biosystemThe phosphatidylinositol 3' -kinase(PI3K)-Akt signaling pathway is activated by many types of cellular stimuli or toxic insults and regulates fundamental cellular functions such as transcription, tra...
    • Rap1 signaling pathway, organism-specific biosystem (from KEGG)
      Rap1 signaling pathway, organism-specific biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
    • Rap1 signaling pathway, conserved biosystem (from KEGG)
      Rap1 signaling pathway, conserved biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
    • Ras signaling pathway, organism-specific biosystem (from KEGG)
      Ras signaling pathway, organism-specific biosystemThe Ras proteins are GTPases that function as molecular switches for signaling pathways regulating cell proliferation, survival, growth, migration, differentiation or cytoskeletal dynamism. Ras prote...

    General gene information

    Homology

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006589.3 Reference CanFam3.1 Primary Assembly

      Range
      42373197..42381161 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005622755.3XP_005622812.1  ephrin-A1 isoform X3

      See identical proteins and their annotated locations for XP_005622812.1

      Conserved Domains (1) summary
      cd10425
      Location:2111
      Ephrin-A_Ectodomain; Ectodomain of Ephrin A
    2. XM_846978.5XP_852071.1  ephrin-A1 isoform X2

      UniProtKB/TrEMBL
      E2QUE4
      Related
      ENSCAFP00000025132.1, ENSCAFT00000027032.1
      Conserved Domains (1) summary
      cd10425
      Location:19148
      Ephrin-A_Ectodomain; Ectodomain of Ephrin A
    3. XM_005622756.3XP_005622813.1  ephrin-A1 isoform X3

      See identical proteins and their annotated locations for XP_005622813.1

      Conserved Domains (1) summary
      cd10425
      Location:2111
      Ephrin-A_Ectodomain; Ectodomain of Ephrin A
    4. XM_005622754.3XP_005622811.1  ephrin-A1 isoform X3

      See identical proteins and their annotated locations for XP_005622811.1

      Conserved Domains (1) summary
      cd10425
      Location:2111
      Ephrin-A_Ectodomain; Ectodomain of Ephrin A
    5. XM_014115357.2XP_013970832.1  ephrin-A1 isoform X1

      Conserved Domains (1) summary
      cd10425
      Location:79200
      Ephrin-A_Ectodomain; Ectodomain of Ephrin A
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