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    TRIM37 tripartite motif containing 37 [ Canis lupus familiaris (dog) ]

    Gene ID: 480575, updated on 26-Sep-2018

    Summary

    Official Symbol
    TRIM37provided by VGNC
    Official Full Name
    tripartite motif containing 37provided by VGNC
    Primary source
    VGNC:VGNC:47818
    See related
    Ensembl:ENSCAFG00000017569
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Orthologs

    Genomic context

    See TRIM37 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 9 NC_006591.3 (33446903..33687650, complement)

    Chromosome 9 - NC_006591.3Genomic Context describing neighboring genes Neighboring gene RAD51 paralog C Neighboring gene protein phosphatase, Mg2+/Mn2+ dependent 1E Neighboring gene calmodulin 2 (phosphorylase kinase, delta) pseudogene Neighboring gene uncharacterized LOC111097410 Neighboring gene spindle and kinetochore associated complex subunit 2 Neighboring gene microRNA mir-454

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006591.3 Chromosome 9 Reference CanFam3.1 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Ubiquitin mediated proteolysis, organism-specific biosystem (from KEGG)
      Ubiquitin mediated proteolysis, organism-specific biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...
    • Ubiquitin mediated proteolysis, conserved biosystem (from KEGG)
      Ubiquitin mediated proteolysis, conserved biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase TRIM37
    XP_013972191.1
    XP_022278932.1
    XP_022278933.1
    XP_022278934.1
    XP_022278935.1
    XP_022278936.1
    XP_022278937.1
    XP_022278938.1
    XP_022278939.1
    XP_537697.3

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006591.3 Reference CanFam3.1 Primary Assembly

      Range
      33446903..33687650 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_014116716.2XP_013972191.1  E3 ubiquitin-protein ligase TRIM37 isoform X7

      Related
      ENSCAFP00000025908.3, ENSCAFT00000027859.4
      Conserved Domains (4) summary
      smart00502
      Location:132254
      BBC; B-Box C-terminal domain
      cd00162
      Location:1558
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd03773
      Location:273406
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      pfam00643
      Location:90132
      zf-B_box; B-box zinc finger
    2. XM_022423228.1XP_022278936.1  E3 ubiquitin-protein ligase TRIM37 isoform X5

      Conserved Domains (4) summary
      smart00502
      Location:132254
      BBC; B-Box C-terminal domain
      smart00336
      Location:91132
      BBOX; B-Box-type zinc finger
      cd03773
      Location:273431
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:1355
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins
    3. XM_022423230.1XP_022278938.1  E3 ubiquitin-protein ligase TRIM37 isoform X9

      Conserved Domains (4) summary
      smart00502
      Location:114236
      BBC; B-Box C-terminal domain
      smart00336
      Location:73114
      BBOX; B-Box-type zinc finger
      cd03773
      Location:255413
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:137
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins
    4. XM_022423225.1XP_022278933.1  E3 ubiquitin-protein ligase TRIM37 isoform X2

      Conserved Domains (4) summary
      smart00502
      Location:114236
      BBC; B-Box C-terminal domain
      smart00336
      Location:73114
      BBOX; B-Box-type zinc finger
      cd03773
      Location:255413
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:137
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins
    5. XM_022423224.1XP_022278932.1  E3 ubiquitin-protein ligase TRIM37 isoform X1

      Conserved Domains (4) summary
      smart00502
      Location:114236
      BBC; B-Box C-terminal domain
      smart00336
      Location:73114
      BBOX; B-Box-type zinc finger
      cd03773
      Location:255413
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:137
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins
    6. XM_022423226.1XP_022278934.1  E3 ubiquitin-protein ligase TRIM37 isoform X3

      Conserved Domains (5) summary
      smart00502
      Location:141263
      BBC; B-Box C-terminal domain
      smart00336
      Location:100141
      BBOX; B-Box-type zinc finger
      cd03773
      Location:282440
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:2264
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins
      cl28410
      Location:6104
      RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]
    7. XM_022423229.1XP_022278937.1  E3 ubiquitin-protein ligase TRIM37 isoform X6

      Conserved Domains (4) summary
      smart00502
      Location:114236
      BBC; B-Box C-terminal domain
      smart00336
      Location:73114
      BBOX; B-Box-type zinc finger
      cd03773
      Location:255388
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:137
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins
    8. XM_022423231.1XP_022278939.1  E3 ubiquitin-protein ligase TRIM37 isoform X10

      Conserved Domains (2) summary
      cd03773
      Location:86244
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cl25407
      Location:167
      ClassIIa_HDAC_Gln-rich-N; Glutamine-rich N-terminal helical domain of various Class IIa histone deacetylases (HDAC4, HDAC5 and HDCA9)
    9. XM_022423227.1XP_022278935.1  E3 ubiquitin-protein ligase TRIM37 isoform X4

      Conserved Domains (4) summary
      smart00502
      Location:114236
      BBC; B-Box C-terminal domain
      smart00336
      Location:73114
      BBOX; B-Box-type zinc finger
      cd03773
      Location:255413
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      cd16619
      Location:137
      mRING-HC-C4C4_TRIM37_C-VIII; Modified RING finger, HC subclass (C4C4-type), found in tripartite motif-containing protein 37 (TRIM37) and similar proteins
    10. XM_537697.6XP_537697.3  E3 ubiquitin-protein ligase TRIM37 isoform X8

      See identical proteins and their annotated locations for XP_537697.3

      UniProtKB/TrEMBL
      E2RKB8
      Conserved Domains (4) summary
      smart00502
      Location:132254
      BBC; B-Box C-terminal domain
      cd00162
      Location:1558
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cd03773
      Location:273406
      MATH_TRIM37; Tripartite motif containing protein 37 (TRIM37) family, MATH domain; TRIM37 is a peroxisomal protein and is a member of the tripartite motif (TRIM) protein subfamily, also known as the RING-B-box-coiled-coil (RBCC) subfamily of zinc-finger proteins. ...
      pfam00643
      Location:90132
      zf-B_box; B-box zinc finger
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