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    ARRB2 arrestin beta 2 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 454450, updated on 20-Apr-2019

    Summary

    Official Symbol
    ARRB2provided by VGNC
    Official Full Name
    arrestin beta 2provided by VGNC
    Primary source
    VGNC:VGNC:9221
    Locus tag
    CK820_G0036945
    See related
    Ensembl:ENSPTRG00000008601
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs

    Genomic context

    See ARRB2 in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    105 current Clint_PTRv2 (GCF_002880755.1) 17 NC_036896.1 (4418823..4429618)
    104 previous assembly Pan_tro 3.0 (GCF_000001515.7) 17 NC_006484.4 (4905797..4916612)
    103 previous assembly Pan_troglodytes-2.1.4 (GCF_000001515.6) 17 NC_006484.3 (4734271..4745515)

    Chromosome 17 - NC_036896.1Genomic Context describing neighboring genes Neighboring gene proline, glutamate and leucine rich protein 1 Neighboring gene uncharacterized LOC112206026 Neighboring gene 40S ribosomal protein S12 pseudogene Neighboring gene mediator complex subunit 11 Neighboring gene C-X-C motif chemokine ligand 16 Neighboring gene zinc finger MYND-type containing 15

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Calcium Regulation in the Cardiac Cell, organism-specific biosystem (from WikiPathways)
      Calcium Regulation in the Cardiac Cell, organism-specific biosystemCalcium is a common signaling mechanism, as once it enters the cytoplasm it exerts allosteric regulatory affects on many enzymes and proteins. Calcium can act in signal transduction after influx resu...
    • Chemokine signaling pathway, organism-specific biosystem (from KEGG)
      Chemokine signaling pathway, organism-specific biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
    • Chemokine signaling pathway, conserved biosystem (from KEGG)
      Chemokine signaling pathway, conserved biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
    • Endocytosis, organism-specific biosystem (from KEGG)
      Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Endocytosis, conserved biosystem (from KEGG)
      Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Hedgehog signaling pathway, organism-specific biosystem (from KEGG)
      Hedgehog signaling pathway, organism-specific biosystemThe Hedgehog (Hh) signaling pathway has numerous roles in the control of cell proliferation, tissue patterning, stem cell maintenance and development. The primary cilium is an important center for tr...
    • Hedgehog signaling pathway, conserved biosystem (from KEGG)
      Hedgehog signaling pathway, conserved biosystemThe Hedgehog (Hh) signaling pathway has numerous roles in the control of cell proliferation, tissue patterning, stem cell maintenance and development. The primary cilium is an important center for tr...
    • MAPK signaling pathway, organism-specific biosystem (from KEGG)
      MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • MAPK signaling pathway, organism-specific biosystem (from WikiPathways)
      MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • MAPK signaling pathway, conserved biosystem (from KEGG)
      MAPK signaling pathway, conserved biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • Morphine addiction, organism-specific biosystem (from KEGG)
      Morphine addiction, organism-specific biosystemMorphine is an alkaloid from the plant extracts of opium poppy. Although morphine is highly effective for the treatment of pain, it is also known to be intensely addictive. We now know that the most ...
    • Morphine addiction, conserved biosystem (from KEGG)
      Morphine addiction, conserved biosystemMorphine is an alkaloid from the plant extracts of opium poppy. Although morphine is highly effective for the treatment of pain, it is also known to be intensely addictive. We now know that the most ...
    • Olfactory transduction, organism-specific biosystem (from KEGG)
      Olfactory transduction, organism-specific biosystemWithin the compact cilia of the olfactory receptor neurons (ORNs) a cascade of enzymatic activity transduces the binding of an odorant molecule to a receptor into an electrical signal that can be tra...
    • Olfactory transduction, conserved biosystem (from KEGG)
      Olfactory transduction, conserved biosystemWithin the compact cilia of the olfactory receptor neurons (ORNs) a cascade of enzymatic activity transduces the binding of an odorant molecule to a receptor into an electrical signal that can be tra...

    General gene information

    Markers

    Homology

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Pan troglodytes Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Clint_PTRv2 Primary Assembly

    Genomic

    1. NC_036896.1 Reference Clint_PTRv2 Primary Assembly

      Range
      4418823..4429618
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_016931274.1XP_016786763.1  beta-arrestin-2 isoform X1

      Related
      ENSPTRP00000014687.6, ENSPTRT00000015872.6
      Conserved Domains (2) summary
      smart01017
      Location:215370
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:19196
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    2. XM_024350190.1XP_024205958.1  beta-arrestin-2 isoform X3

      Conserved Domains (2) summary
      smart01017
      Location:215356
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:19196
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    3. XM_009431656.2XP_009429931.1  beta-arrestin-2 isoform X2

      See identical proteins and their annotated locations for XP_009429931.1

      UniProtKB/TrEMBL
      H2QBY1
      Related
      ENSPTRP00000071240.1, ENSPTRT00000107637.1
      Conserved Domains (2) summary
      smart01017
      Location:194349
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:19175
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    4. XM_024350191.1XP_024205959.1  beta-arrestin-2 isoform X4

      Conserved Domains (1) summary
      smart01017
      Location:2157
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
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