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    PLA2G1B phospholipase A2 group IB [ Sus scrofa (pig) ]

    Gene ID: 445525, updated on 18-Apr-2019

    Summary

    Gene symbol
    PLA2G1B
    Gene description
    phospholipase A2 group IB
    See related
    Ensembl:ENSSSCG00000029501
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus
    Also known as
    PLA2; sPLA(2)-IB
    Annotation information
    Annotation category: partial on reference assembly
    Expression
    Biased expression in lung (RPKM 12.4), mixtures (RPKM 2.0) and 1 other tissue See more
    Orthologs

    Genomic context

    See PLA2G1B in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 14 NC_010456.5 (40314520..40322315, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 14 NC_010456.4 (42821332..42829127)

    Chromosome 14 - NC_010456.5Genomic Context describing neighboring genes Neighboring gene paxillin Neighboring gene uncharacterized LOC102165911 Neighboring gene sirtuin 4 Neighboring gene musashi RNA binding protein 1 Neighboring gene cytochrome c oxidase subunit VIa polypeptide 1

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    bile acid binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phospholipase A2 activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) IEA
    Inferred from Electronic Annotation
    more info
     
    phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) IEA
    Inferred from Electronic Annotation
    more info
     
    signaling receptor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    signaling receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    activation of MAPK activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT arachidonic acid secretion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to insulin stimulus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    fatty acid biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT interleukin-1 production IDA
    Inferred from Direct Assay
    more info
    PubMed 
    interleukin-8 production IDA
    Inferred from Direct Assay
    more info
    PubMed 
    intracellular signal transduction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    leukotriene biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    neutrophil chemotaxis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    neutrophil mediated immunity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of NF-kappaB transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of calcium ion transport into cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of cell proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of fibroblast proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of immune response IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of glucose import IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    phospholipase A2, major isoenzyme
    Names
    group IB phospholipase A2
    group IB secretory phospholipase A(2)
    phosphatidylcholine 2-acylhydrolase 1B
    phospholipase A2, group IB (pancreas)
    NP_001004037.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004037.1NP_001004037.1  phospholipase A2, major isoenzyme precursor

      See identical proteins and their annotated locations for NP_001004037.1

      Status: PROVISIONAL

      Source sequence(s)
      M21055
      UniProtKB/Swiss-Prot
      P00592
      Related
      ENSSSCP00000028002.1, ENSSSCT00000031208.2
      Conserved Domains (1) summary
      smart00085
      Location:24146
      PA2c; Phospholipase A2

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010456.5 Reference Sscrofa11.1 Primary Assembly

      Range
      40314520..40322315 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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