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    ADCYAP1 adenylate cyclase activating polypeptide 1 [ Sus scrofa (pig) ]

    Gene ID: 414283, updated on 3-Feb-2019

    Summary

    Gene symbol
    ADCYAP1
    Gene description
    adenylate cyclase activating polypeptide 1
    See related
    Ensembl:ENSSSCG00000035186
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus
    Also known as
    PACAP
    Expression
    Low expression observed in reference dataset See more
    Orthologs

    Genomic context

    See ADCYAP1 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 6 NC_010448.4 (105414628..105422294, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 6 NC_010448.3 (98531534..98539159, complement)

    Chromosome 6 - NC_010448.4Genomic Context describing neighboring genes Neighboring gene classical arabinogalactan protein 9-like Neighboring gene uncharacterized LOC102163958 Neighboring gene uncharacterized LOC102165393 Neighboring gene glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1-like Neighboring gene YES proto-oncogene 1, Src family tyrosine kinase

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    neuropeptide hormone activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    peptide hormone receptor binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    pituitary adenylate cyclase activating polypeptide activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    pituitary adenylate cyclase-activating polypeptide receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    adenylate cyclase-activating G protein-coupled receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cAMP-mediated signaling ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    insulin secretion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    neuron projection development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    neuropeptide signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of ERK1 and ERK2 cascade ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of cytosolic calcium ion concentration ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of gene expression ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of growth hormone secretion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of protein kinase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of G protein-coupled receptor signaling pathway ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of protein localization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    pituitary adenylate cyclase-activating polypeptide
    Names
    adenylate cyclase activating peptide, pituitary 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001001544.1NP_001001544.1  pituitary adenylate cyclase-activating polypeptide precursor

      See identical proteins and their annotated locations for NP_001001544.1

      Status: PROVISIONAL

      Source sequence(s)
      AJ715856
      UniProtKB/Swiss-Prot
      P41535
      Related
      ENSSSCP00000004005.3, ENSSSCT00000004097.3
      Conserved Domains (1) summary
      pfam00123
      Location:132158
      Hormone_2; Peptide hormone

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010448.4 Reference Sscrofa11.1 Primary Assembly

      Range
      105414628..105422294 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005665307.3XP_005665364.1  pituitary adenylate cyclase-activating polypeptide isoform X1

      UniProtKB/TrEMBL
      A0A287BEZ0
      Related
      ENSSSCP00000054892.1, ENSSSCT00000055920.1
      Conserved Domains (1) summary
      pfam00123
      Location:132158
      Hormone_2; Peptide hormone
    2. XM_021093591.1XP_020949250.1  pituitary adenylate cyclase-activating polypeptide isoform X1

      Conserved Domains (1) summary
      pfam00123
      Location:132158
      Hormone_2; Peptide hormone
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