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    dlg4b discs, large homolog 4b (Drosophila) [ Danio rerio (zebrafish) ]

    Gene ID: 405796, updated on 14-Feb-2019

    Summary

    Official Symbol
    dlg4bprovided by ZNC
    Official Full Name
    discs, large homolog 4b (Drosophila)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040628-3
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    dlg4
    Annotation information
    Annotation category: partial on reference assembly

    Genomic context

    See dlg4b in Genome Data Viewer
    Location:
    chromosome: 23
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 23 NC_007134.7 (44263986..44333064)
    105 previous assembly GRCz10 (GCF_000002035.5) 23 NC_007134.6 (44334104..44527660)
    103 previous assembly Zv9 (GCF_000002035.4) 23 NC_007134.5 (44280347..44306993) , (44434637..44459695)

    Chromosome 23 - NC_007134.7Genomic Context describing neighboring genes Neighboring gene zgc:158659 Neighboring gene si:ch1073-157b13.1 Neighboring gene eph receptor B4b Neighboring gene eukaryotic translation initiation factor 4E family member 2 related sequence 1

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    ionotropic glutamate receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein heterodimerization activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cell-cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chemical synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    receptor clustering IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    receptor localization to synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cell junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with ionotropic glutamate receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    neuromuscular junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    postsynaptic density ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    postsynaptic density membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    disks large homolog 4
    Names
    PSD-95
    PSD95/SAP90
    discs, large homolog 4
    postsynaptic density protein 95

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_214728.1NP_999893.1  disks large homolog 4

      See identical proteins and their annotated locations for NP_999893.1

      Status: PROVISIONAL

      Source sequence(s)
      AY520570
      UniProtKB/Swiss-Prot
      Q6R005
      Conserved Domains (9) summary
      smart00072
      Location:617788
      GuKc; Guanylate kinase homologues
      smart00228
      Location:245331
      PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
      cd00992
      Location:391471
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam00595
      Location:153237
      PDZ; PDZ domain (Also known as DHR or GLGF)
      pfam00625
      Location:609788
      Guanylate_kin; Guanylate kinase
      pfam09058
      Location:458
      L27_1; L27_1
      pfam10600
      Location:342392
      PDZ_assoc; PDZ-associated domain of NMDA receptors
      pfam10608
      Location:71152
      MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK
      cl17036
      Location:509574
      SH3; Src Homology 3 domain superfamily

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007134.7 Reference GRCz11 Primary Assembly

      Range
      44263986..44333064
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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