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    POU1F1 POU class 1 homeobox 1 [ Canis lupus familiaris (dog) ]

    Gene ID: 403753, updated on 2-Oct-2018

    Summary

    Official Symbol
    POU1F1provided by VGNC
    Official Full Name
    POU class 1 homeobox 1provided by VGNC
    Primary source
    VGNC:VGNC:44824
    See related
    Ensembl:ENSCAFG00000007781
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Canis lupus familiaris (sub-species: familiaris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
    Also known as
    PIT-1
    Orthologs

    Genomic context

    See POU1F1 in Genome Data Viewer
    Location:
    chromosome: 31
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    105 current CanFam3.1 (GCF_000002285.3) 31 NC_006613.3 (769454..788761)

    Chromosome 31 - NC_006613.3Genomic Context describing neighboring genes Neighboring gene 5-hydroxytryptamine receptor 1F Neighboring gene uncharacterized LOC102152058 Neighboring gene uncharacterized LOC111093453 Neighboring gene charged multivesicular body protein 2B Neighboring gene alcohol dehydrogenase class-3 pseudogene

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_006613.3 Chromosome 31 Reference CanFam3.1 Primary Assembly

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    DNA-binding transcription factor activity, RNA polymerase II-specific ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    positive regulation of transcription by RNA polymerase II ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    pituitary-specific positive transcription factor 1
    Names
    GHF-1
    POU domain, class 1, transcription factor 1 (Pit1, growth hormone factor 1)
    growth hormone factor 1
    pituitary specific transcription factor 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001006949.1NP_001006950.1  pituitary-specific positive transcription factor 1

      See identical proteins and their annotated locations for NP_001006950.1

      Status: PROVISIONAL

      Source sequence(s)
      AF035585
      UniProtKB/Swiss-Prot
      Q9TTI7
      Related
      ENSCAFP00000011512.2, ENSCAFT00000012423.2
      Conserved Domains (2) summary
      smart00352
      Location:125198
      POU; Found in Pit-Oct-Unc transcription factors
      pfam00046
      Location:217270
      Homeobox; Homeobox domain

    RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 105 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CanFam3.1 Primary Assembly

    Genomic

    1. NC_006613.3 Reference CanFam3.1 Primary Assembly

      Range
      769454..788761
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_022413060.1XP_022268768.1  pituitary-specific positive transcription factor 1 isoform X1

      Conserved Domains (2) summary
      pfam00046
      Location:162215
      Homeobox; Homeobox domain
      cl22952
      Location:125154
      Pou; Pou domain - N-terminal to homeobox domain
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