Format

Send to:

Choose Destination
    • Showing Current items.

    Atf-2 Activating transcription factor-2 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37978, updated on 10-Jan-2019

    Summary

    Official Symbol
    Atf-2provided by FlyBase
    Official Full Name
    Activating transcription factor-2provided by FlyBase
    Primary source
    FLYBASE:FBgn0265193
    Locus tag
    Dmel_CG44246
    Gene type
    protein coding
    RNA name
    activating transcription factor-2
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster (old-lineage: Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Holometabola; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    atf-2; ATF-2; Atf2; ATF2; CG12850; CG30420; CG44246; dATF-2; dATF2; DM5; Dmel\CG44246
    Old locus tag
    Dmel_CG30420

    Genomic context

    See Atf-2 in Genome Data Viewer
    Location:
    60E4-60E4; 2-107 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.18 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (24870108..24871509)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (20757631..20759032)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Bibliography

    Related articles in PubMed

    Pathways from BioSystems

    • MAPK signaling pathway - fly, organism-specific biosystem (from KEGG)
      MAPK signaling pathway - fly, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) signaling cascades that are highly conserved from yeast to mammals use protein phosphorylation to convey signals intracellularly, and play a crucial role i...
    • MAPK signaling pathway - fly, conserved biosystem (from KEGG)
      MAPK signaling pathway - fly, conserved biosystemThe mitogen-activated protein kinase (MAPK) signaling cascades that are highly conserved from yeast to mammals use protein phosphorylation to convey signals intracellularly, and play a crucial role i...
    • Toll and Imd signaling pathway, organism-specific biosystem (from KEGG)
      Toll and Imd signaling pathway, organism-specific biosystemInsects, such as Drosophila, have evolved complex mechanisms to combat microbial infection. TOLL and IMD pathways are responsible for the immune response that functions through the production of anti...
    • Toll and Imd signaling pathway, conserved biosystem (from KEGG)
      Toll and Imd signaling pathway, conserved biosystemInsects, such as Drosophila, have evolved complex mechanisms to combat microbial infection. TOLL and IMD pathways are responsible for the immune response that functions through the production of anti...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    cellular response to heat IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cellular response to osmotic stress IDA
    Inferred from Direct Assay
    more info
    PubMed 
    heterochromatin maintenance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mucosal immune response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of heterochromatin assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of triglyceride biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    sleep IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    stress-activated MAPK cascade IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    nuclear pericentric heterochromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    polytene chromosome band IDA
    Inferred from Direct Assay
    more info
    PubMed 
    polytene chromosome chromocenter IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    activating transcription factor-2
    Names
    Atf-2-PA
    CG44246-PA

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      24870108..24871509
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001038884.2NP_001033973.1  activating transcription factor-2 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001033973.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2PE13
      Related
      FBpp0308241, FBtr0339096
      Conserved Domains (1) summary
      pfam07989
      Location:300336
      Cnn_1N; Centrosomin N-terminal motif 1
    Support Center