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    atg3 autophagy related 3 [ Danio rerio (zebrafish) ]

    Gene ID: 336632, updated on 14-Feb-2019

    Summary

    Official Symbol
    atg3provided by ZNC
    Official Full Name
    autophagy related 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8576
    See related
    Ensembl:ENSDARG00000009350
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Danio
    Also known as
    apg3l; zgc:64156; im:6910145; wu:fb15g12
    Orthologs

    Genomic context

    See atg3 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (7109962..7123169, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (6952793..6966000, complement)
    103 previous assembly Zv9 (GCF_000002035.4) 6 NC_007117.5 (7026777..7039984, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene Indian hedgehog signaling molecule b Neighboring gene nonhomologous end-joining factor 1 Neighboring gene si:ch211-237c6.4 Neighboring gene heparan sulfate 6-O-sulfotransferase 3a

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Autophagy - animal, organism-specific biosystem (from KEGG)
      Autophagy - animal, organism-specific biosystemAutophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily cons...
    • Autophagy - animal, conserved biosystem (from KEGG)
      Autophagy - animal, conserved biosystemAutophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, organelle turnover, and non-selective breakdown of cytoplasmic components, which is evolutionarily cons...
    • Autophagy - other, organism-specific biosystem (from KEGG)
      Autophagy - other, organism-specific biosystemAutophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and is characterized by the formation of a double-membrane structure called the autophagosome, either ...
    • Autophagy - other, conserved biosystem (from KEGG)
      Autophagy - other, conserved biosystemAutophagy is a degradative pathway for the removal of cytoplasmic materials in eukaryotic cells, and is characterized by the formation of a double-membrane structure called the autophagosome, either ...
    • Cellular responses to stress, organism-specific biosystem (from REACTOME)
      Cellular responses to stress, organism-specific biosystemcomputationally inferred pathway (not manually curated)
    • Macroautophagy, organism-specific biosystem (from REACTOME)
      Macroautophagy, organism-specific biosystemcomputationally inferred pathway (not manually curated)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    Atg12 transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Atg8 ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Atg8 ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    autophagosome assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    autophagy of mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitochondrial fragmentation involved in apoptotic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    ubiquitin-like-conjugating enzyme ATG3
    Names
    APG3 autophagy 3-like
    APG3-like
    autophagy-related protein 3
    NP_956316.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200022.1NP_956316.1  ubiquitin-like-conjugating enzyme ATG3

      See identical proteins and their annotated locations for NP_956316.1

      Status: PROVISIONAL

      Source sequence(s)
      BC057434
      UniProtKB/Swiss-Prot
      Q6PFS7
      Related
      ENSDARP00000041303.7, ENSDART00000041304.8
      Conserved Domains (3) summary
      pfam03986
      Location:8133
      Autophagy_N; Autophagocytosis associated protein (Atg3), N-terminal domain
      pfam03987
      Location:207268
      Autophagy_act_C; Autophagocytosis associated protein, active-site domain
      pfam10381
      Location:289312
      Autophagy_C; Autophagocytosis associated protein C-terminal

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      7109962..7123169 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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