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    Agtrap angiotensin II receptor-associated protein [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298646, updated on 18-Apr-2019

    Summary

    Official Symbol
    Agtrapprovided by RGD
    Official Full Name
    angiotensin II receptor-associated proteinprovided by RGD
    Primary source
    RGD:1359346
    See related
    Ensembl:ENSRNOG00000008619
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Expression
    Biased expression in Kidney (RPKM 115.0), Adrenal (RPKM 29.2) and 9 other tissues See more
    Orthologs

    Genomic context

    See Agtrap in Genome Data Viewer
    Location:
    5q36
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (164888069..164898387, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 5 NC_005104.3 (168546202..168556520, complement)

    Chromosome 5 - NC_005104.4Genomic Context describing neighboring genes Neighboring gene NHP2-like protein 1-like Neighboring gene uncharacterized LOC102551309 Neighboring gene uncharacterized LOC102551534 Neighboring gene uncharacterized LOC102551596

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Angiotensin signaling in thick ascending limbs, organism-specific biosystem (from WikiPathways)
      Angiotensin signaling in thick ascending limbs, organism-specific biosystemThe thick ascending limb of the loop pf Henle reabsorbs 25 to 30 % of the NaCl filtered through the glomerulus. Abnormally elevated Na reabsorption by this segment is link to salt-sensitive hypertens...

    General gene information

    Markers

    Homology

    Clone Names

    • MGC95145

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    angiotensin type II receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    angiotensin type II receptor activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    angiotensin-activated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of blood pressure IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of blood pressure ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    response to hypoxia IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    cell cortex IEA
    Inferred from Electronic Annotation
    more info
     
    cell cortex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cellular_component ND
    No biological Data available
    more info
     
    cytoplasmic vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    type-1 angiotensin II receptor-associated protein
    Names
    AT1 receptor-associated protein
    angiotensin II, type I receptor-associated protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007654.1NP_001007655.1  type-1 angiotensin II receptor-associated protein

      See identical proteins and their annotated locations for NP_001007655.1

      Status: PROVISIONAL

      Source sequence(s)
      BC082019
      UniProtKB/Swiss-Prot
      Q642A2
      Related
      ENSRNOP00000011747.3, ENSRNOT00000011747.6
      Conserved Domains (1) summary
      smart00805
      Location:1160
      AGTRAP; Angiotensin II, type I receptor-associated protein

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005104.4 Reference Rnor_6.0 Primary Assembly

      Range
      164888069..164898387 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000073.1 Alternate Rn_Celera

      Range
      156788514..156798832 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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