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    Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293186, updated on 2-Oct-2018

    Summary

    Official Symbol
    Lyve1provided by RGD
    Official Full Name
    lymphatic vessel endothelial hyaluronan receptor 1provided by RGD
    Primary source
    RGD:1310864
    See related
    Ensembl:ENSRNOG00000026902
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Xlkd1
    Expression
    Biased expression in Lung (RPKM 301.8), Liver (RPKM 150.0) and 7 other tissues See more
    Orthologs

    Genomic context

    See Lyve1 in Genome Data Viewer
    Location:
    1q33
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (175663266..175676699, complement)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 1 NC_005100.3 (182650925..182664312, complement)

    Chromosome 1 - NC_005100.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103691204 Neighboring gene adenosine monophosphate deaminase 3 Neighboring gene ring finger protein 141 Neighboring gene murine retrovirus integration site 1 homolog Neighboring gene uncharacterized LOC103691205 Neighboring gene CTR9 homolog, Paf1/RNA polymerase II complex component

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    hyaluronic acid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    hyaluronic acid binding ISO
    Inferred from Sequence Orthology
    more info
     
    transmembrane signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transmembrane signaling receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    glycosaminoglycan catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cell periphery ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    lymphatic vessel endothelial hyaluronic acid receptor 1
    Names
    extra cellular link domain-containing 1
    extracellular link domain-containing 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106286.1NP_001099756.1  lymphatic vessel endothelial hyaluronic acid receptor 1

      See identical proteins and their annotated locations for NP_001099756.1

      Status: PROVISIONAL

      Source sequence(s)
      CH473956
      UniProtKB/TrEMBL
      D3ZD19
      Related
      ENSRNOP00000036731.4, ENSRNOT00000030474.4
      Conserved Domains (1) summary
      cd03516
      Location:62186
      Link_domain_CD44_like; This domain is a hyaluronan (HA)-binding domain. It is found in CD44 receptor and mediates adhesive interactions during inflammatory leukocyte homing and tumor metastasis. It also plays an important role in arteriogenesis. The functional HA-binding ...

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005100.4 Reference Rnor_6.0 Primary Assembly

      Range
      175663266..175676699 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000069.1 Alternate Rn_Celera

      Range
      162853590..162866975 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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