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    Ctdnep1 CTD nuclear envelope phosphatase 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 287447, updated on 18-Apr-2019

    Summary

    Official Symbol
    Ctdnep1provided by RGD
    Official Full Name
    CTD nuclear envelope phosphatase 1provided by RGD
    Primary source
    RGD:1310172
    See related
    Ensembl:ENSRNOG00000017352
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Dullard
    Expression
    Biased expression in Muscle (RPKM 174.6), Spleen (RPKM 98.0) and 9 other tissues See more
    Orthologs

    Genomic context

    See Ctdnep1 in Genome Data Viewer
    Location:
    10q24
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (56590822..56600235)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 10 NC_005109.3 (56335955..56345354)

    Chromosome 10 - NC_005109.4Genomic Context describing neighboring genes Neighboring gene claudin 7 Neighboring gene elongator acetyltransferase complex subunit 5 Neighboring gene GABA type A receptor-associated protein Neighboring gene PHD finger protein 23

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from BioSystems

    General gene information

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    phosphoprotein phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein serine/threonine phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein serine/threonine phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    gamete generation IEA
    Inferred from Electronic Annotation
    more info
     
    gamete generation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    mesoderm development IEA
    Inferred from Electronic Annotation
    more info
     
    mesoderm development ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nuclear envelope organization ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nuclear envelope organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of canonical Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of triglyceride biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    positive regulation of triglyceride biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein dephosphorylation ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein dephosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    protein localization to nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    protein localization to nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    Nem1-Spo7 phosphatase complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Nem1-Spo7 phosphatase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cellular_component ND
    No biological Data available
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    lipid droplet IEA
    Inferred from Electronic Annotation
    more info
     
    lipid droplet ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nuclear envelope ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nuclear membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    CTD nuclear envelope phosphatase 1
    Names
    serine/threonine-protein phosphatase dullard
    NP_001093964.1
    XP_006246705.1
    XP_006246706.1
    XP_017452582.1
    XP_017452583.1
    XP_017452584.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001100494.1NP_001093964.1  CTD nuclear envelope phosphatase 1

      See identical proteins and their annotated locations for NP_001093964.1

      Status: VALIDATED

      Source sequence(s)
      BC107474, BU671232
      UniProtKB/Swiss-Prot
      Q3B7T6
      Related
      ENSRNOP00000023379.4, ENSRNOT00000023379.4
      Conserved Domains (1) summary
      TIGR02251
      Location:61229
      HIF-SF_euk; Dullard-like phosphatase domain

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005109.4 Reference Rnor_6.0 Primary Assembly

      Range
      56590822..56600235
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017597093.1XP_017452582.1  CTD nuclear envelope phosphatase 1 isoform X1

    2. XM_017597094.1XP_017452583.1  CTD nuclear envelope phosphatase 1 isoform X2

    3. XM_017597095.1XP_017452584.1  CTD nuclear envelope phosphatase 1 isoform X5

    4. XM_006246643.3XP_006246705.1  CTD nuclear envelope phosphatase 1 isoform X3

      Conserved Domains (2) summary
      COG5190
      Location:167346
      FCP1; TFIIF-interacting CTD phosphatase, includes NLI-interacting factor [Transcription]
      TIGR02251
      Location:168340
      HIF-SF_euk; Dullard-like phosphatase domain
    5. XM_006246644.3XP_006246706.1  CTD nuclear envelope phosphatase 1 isoform X4

      Conserved Domains (2) summary
      COG5190
      Location:167342
      FCP1; TFIIF-interacting CTD phosphatase, includes NLI-interacting factor [Transcription]
      TIGR02251
      Location:168336
      HIF-SF_euk; Dullard-like phosphatase domain

    Alternate Rn_Celera

    Genomic

    1. AC_000078.1 Alternate Rn_Celera

      Range
      53858610..53867366
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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