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    PCSK1 proprotein convertase subtilisin/kexin type 1 [ Bos taurus (cattle) ]

    Gene ID: 281967, updated on 26-Feb-2019

    Summary

    Official Symbol
    PCSK1provided by VGNC
    Official Full Name
    proprotein convertase subtilisin/kexin type 1provided by VGNC
    Primary source
    VGNC:VGNC:32646
    See related
    BGD:BT11120; Ensembl:ENSBTAG00000020843
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    PC1; PC3
    Orthologs

    Genomic context

    See PCSK1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 7 NC_037334.1 (95746303..95790110, complement)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 7 AC_000164.1 (98155674..98199484, complement)

    Chromosome 7 - NC_037334.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107132664 Neighboring gene selenoprotein I pseudogene Neighboring gene uncharacterized LOC104968993 Neighboring gene calpastatin Neighboring gene endoplasmic reticulum aminopeptidase 1

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    transport vesicle IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    neuroendocrine convertase 1
    Names
    NEC 1
    prohormone convertase 1
    prohormone convertase 3
    proprotein convertase 1
    NP_776837.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174412.2NP_776837.1  neuroendocrine convertase 1 precursor

      See identical proteins and their annotated locations for NP_776837.1

      Status: PROVISIONAL

      Source sequence(s)
      AF186405
      UniProtKB/Swiss-Prot
      Q9GLR1
      Related
      ENSBTAP00000027775.4, ENSBTAT00000027775.5
      Conserved Domains (5) summary
      cd04059
      Location:121415
      Peptidases_S8_Protein_convertases_Kexins_Furin-like; Peptidase S8 family domain in Protein convertases
      pfam00082
      Location:158432
      Peptidase_S8; Subtilase family
      pfam01483
      Location:504591
      P_proprotein; Proprotein convertase P-domain
      pfam12177
      Location:715751
      Proho_convert; Prohormone convertase enzyme
      pfam16470
      Location:34110
      S8_pro-domain; Peptidase S8 pro-domain

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037334.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      95746303..95790110 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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