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    EZR ezrin [ Bos taurus (cattle) ]

    Gene ID: 281574, updated on 14-Apr-2019

    Summary

    Official Symbol
    EZRprovided by VGNC
    Official Full Name
    ezrinprovided by VGNC
    Primary source
    VGNC:VGNC:28676
    See related
    BGD:BT11131; Ensembl:ENSBTAG00000010347
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    VIL2
    Orthologs

    Genomic context

    See EZR in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current ARS-UCD1.2 (GCF_002263795.1) 9 NC_037336.1 (95156270..95202282, complement)
    105 previous assembly Bos_taurus_UMD_3.1.1 (GCF_000003055.6) 9 AC_000166.1 (96598243..96644249, complement)

    Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene synaptotagmin like 3 Neighboring gene uncharacterized LOC112448087 Neighboring gene uncharacterized LOC104969640 Neighboring gene radial spoke head 3 Neighboring gene uncharacterized LOC107132793 Neighboring gene 40S ribosomal protein S15a pseudogene

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    actin filament binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cell adhesion molecule binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    actin filament bundle assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    establishment or maintenance of apical/basal cell polarity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    actin cytoskeleton ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    actin filament ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    apical part of cell ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    apical plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    basolateral plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cell cortex IEA
    Inferred from Electronic Annotation
    more info
     
    ciliary basal body ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    extrinsic component of membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    invadopodium ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    microvillus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    microvillus membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    ruffle membrane IEA
    Inferred from Electronic Annotation
    more info
     
    uropod ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    ezrin
    Names
    cytovillin
    p81
    villin 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174217.2NP_776642.1  ezrin

      See identical proteins and their annotated locations for NP_776642.1

      Status: PROVISIONAL

      Source sequence(s)
      BC102573
      UniProtKB/Swiss-Prot
      P31976
      Related
      ENSBTAP00000013663.4, ENSBTAT00000013663.5
      Conserved Domains (4) summary
      smart00295
      Location:7206
      B41; Band 4.1 homologues
      cd13194
      Location:200296
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:338581
      ERM; Ezrin/radixin/moesin family
      cl25632
      Location:295372
      type_I_hlyD; type I secretion membrane fusion protein, HlyD family

    RefSeqs of Annotated Genomes: Bos taurus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD1.2 Primary Assembly

    Genomic

    1. NC_037336.1 Reference ARS-UCD1.2 Primary Assembly

      Range
      95156270..95202282 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010800726.3XP_010799028.1  ezrin isoform X1

      See identical proteins and their annotated locations for XP_010799028.1

      UniProtKB/Swiss-Prot
      P31976
      Conserved Domains (4) summary
      smart00295
      Location:7206
      B41; Band 4.1 homologues
      cd13194
      Location:200296
      FERM_C_ERM; FERM domain C-lobe/F3 of the ERM family
      pfam00769
      Location:338581
      ERM; Ezrin/radixin/moesin family
      cl25632
      Location:295372
      type_I_hlyD; type I secretion membrane fusion protein, HlyD family
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