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    Hcst hematopoietic cell signal transducer [ Mus musculus (house mouse) ]

    Gene ID: 23900, updated on 19-Feb-2019

    Summary

    Official Symbol
    Hcstprovided by MGI
    Official Full Name
    hematopoietic cell signal transducerprovided by MGI
    Primary source
    MGI:MGI:1344360
    See related
    Ensembl:ENSMUSG00000064109
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DAP10; KAP10
    Expression
    Biased expression in spleen adult (RPKM 65.0), thymus adult (RPKM 46.5) and 8 other tissues See more
    Orthologs

    Genomic context

    See Hcst in Genome Data Viewer
    Location:
    7 B1; 7 17.45 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (30417712..30419854, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (31202731..31204873, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 32029 Neighboring gene TYRO protein tyrosine kinase binding protein Neighboring gene nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta Neighboring gene predicted gene, 30646

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    phosphatidylinositol 3-kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    phosphatidylinositol 3-kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    signaling receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    positive regulation of phosphatidylinositol 3-kinase signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of phosphatidylinositol 3-kinase signaling ISO
    Inferred from Sequence Orthology
    more info
     
    protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of immune response IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    hematopoietic cell signal transducer
    Names
    DNAX-activation protein 10
    membrane protein DAP10
    transmembrane adapter protein KAP10

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011827.3NP_035957.2  hematopoietic cell signal transducer precursor

      See identical proteins and their annotated locations for NP_035957.2

      Status: PROVISIONAL

      Source sequence(s)
      AF172930
      Consensus CDS
      CCDS39882.1
      UniProtKB/Swiss-Prot
      Q9QUJ0
      Related
      ENSMUSP00000074573.3, ENSMUST00000075062.4
      Conserved Domains (1) summary
      pfam07213
      Location:179
      DAP10; DAP10 membrane protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      30417712..30419854 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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