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    Myf6 myogenic factor 6 [ Mus musculus (house mouse) ]

    Gene ID: 17878, updated on 23-Apr-2019

    Summary

    Official Symbol
    Myf6provided by MGI
    Official Full Name
    myogenic factor 6provided by MGI
    Primary source
    MGI:MGI:97253
    See related
    Ensembl:ENSMUSG00000035923
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MRF4; bHLHc4; herculin
    Expression
    Biased expression in mammary gland adult (RPKM 1.9), limb E14.5 (RPKM 1.2) and 7 other tissues See more
    Orthologs

    Genomic context

    See Myf6 in Genome Data Viewer
    Location:
    10 D1; 10 55.96 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (107492860..107494729, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (106929916..106931785, complement)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene lin-7 homolog A (C. elegans) Neighboring gene predicted gene, 36177 Neighboring gene myogenic factor 5 Neighboring gene protein tyrosine phosphatase, receptor type, Q Neighboring gene otogelin-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    muscle organ development IEA
    Inferred from Electronic Annotation
    more info
     
    muscle tissue morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription, DNA-templated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of myoblast differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of myoblast fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of skeletal muscle fiber development IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of transcription, DNA-templated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    skeletal muscle cell differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    skeletal muscle cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    skeletal muscle tissue development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    skeletal muscle tissue development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    skeletal muscle tissue development TAS
    Traceable Author Statement
    more info
    PubMed 
    skeletal muscle tissue regeneration ISO
    Inferred from Sequence Orthology
    more info
     
    somitogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus TAS
    Traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    myogenic factor 6
    Names
    muscle-specific regulatory factor 4

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008657.3NP_032683.1  myogenic factor 6

      See identical proteins and their annotated locations for NP_032683.1

      Status: VALIDATED

      Source sequence(s)
      AC155168
      Consensus CDS
      CCDS24162.1
      UniProtKB/Swiss-Prot
      P15375
      UniProtKB/TrEMBL
      Q0VEJ7
      Related
      ENSMUSP00000047529.3, ENSMUST00000044210.4
      Conserved Domains (2) summary
      pfam00010
      Location:94145
      HLH; Helix-loop-helix DNA-binding domain
      pfam01586
      Location:393
      Basic; Myogenic Basic domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      107492860..107494729 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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