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    Caln1 calneuron 1 [ Mus musculus (house mouse) ]

    Gene ID: 140904, updated on 31-Jan-2019

    Summary

    Official Symbol
    Caln1provided by MGI
    Official Full Name
    calneuron 1provided by MGI
    Primary source
    MGI:MGI:2155987
    See related
    Ensembl:ENSMUSG00000060371
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cabp8; MNCb-0849; 9630012C17Rik
    Expression
    Biased expression in cerebellum adult (RPKM 19.5), cortex adult (RPKM 8.3) and 5 other tissues See more
    Orthologs

    Genomic context

    See Caln1 in Genome Data Viewer
    Location:
    5; 5 G1.3-G2
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (130369356..130846325)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (130845328..131316515)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene SBDS ribosome maturation factor Neighboring gene RIKEN cDNA A330070K13 gene Neighboring gene tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) Neighboring gene predicted gene, 40336 Neighboring gene predicted gene, 40337 Neighboring gene polypeptide N-acetylgalactosaminyltransferase 17 Neighboring gene predicted gene, 40338

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    calcium ion binding ISA
    Inferred from Sequence Alignment
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    trans-Golgi network membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    trans-Golgi network membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    calcium-binding protein 8
    Names
    calneuron I

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021371.2NP_067346.1  calcium-binding protein 8 isoform b

      See identical proteins and their annotated locations for NP_067346.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains a distinct 5' UTR and lacks an in-frame portion of the 5' coding region, compared to variant 1. The resulting protein (isoform 2) has a shorter N-terminus when compared to isoform 1.
      Source sequence(s)
      BC058963, BY274079
      Consensus CDS
      CCDS19714.1
      UniProtKB/Swiss-Prot
      Q9JJG7
      UniProtKB/TrEMBL
      Q542R1
      Related
      ENSMUSP00000106919.2, ENSMUST00000111288.3
      Conserved Domains (1) summary
      cl25352
      Location:32142
      EFh_PEF; The penta-EF hand (PEF) family
    2. NM_181045.1NP_851388.1  calcium-binding protein 8 isoform a

      See identical proteins and their annotated locations for NP_851388.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant represents the longer transcript and it encodes the longer protein (isoform a).
      Source sequence(s)
      AK035865, AK158641, BC058963, BY127416
      Consensus CDS
      CCDS51656.1
      UniProtKB/Swiss-Prot
      Q9JJG7
      UniProtKB/TrEMBL
      F8WHE1, Q542R1, Q8CBJ9
      Related
      ENSMUSP00000083193.3, ENSMUST00000086029.9
      Conserved Domains (1) summary
      cl25352
      Location:74184
      EFh_PEF; The penta-EF hand (PEF) family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      130369356..130846325
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006504369.2XP_006504432.1  calcium-binding protein 8 isoform X2

      See identical proteins and their annotated locations for XP_006504432.1

      Conserved Domains (2) summary
      cd00051
      Location:92153
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:93153
      EF-hand_7; EF-hand domain pair
    2. XM_006504367.2XP_006504430.1  calcium-binding protein 8 isoform X2

      See identical proteins and their annotated locations for XP_006504430.1

      Conserved Domains (2) summary
      cd00051
      Location:92153
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:93153
      EF-hand_7; EF-hand domain pair
    3. XM_006504372.3XP_006504435.1  calcium-binding protein 8 isoform X3

      See identical proteins and their annotated locations for XP_006504435.1

      UniProtKB/TrEMBL
      F8WHE1
      Conserved Domains (1) summary
      cl25352
      Location:74184
      EFh_PEF; The penta-EF hand (PEF) family
    4. XM_006504368.3XP_006504431.1  calcium-binding protein 8 isoform X2

      See identical proteins and their annotated locations for XP_006504431.1

      Conserved Domains (2) summary
      cd00051
      Location:92153
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:93153
      EF-hand_7; EF-hand domain pair
    5. XM_006504374.2XP_006504437.1  calcium-binding protein 8 isoform X4

      See identical proteins and their annotated locations for XP_006504437.1

      UniProtKB/Swiss-Prot
      Q9JJG7
      UniProtKB/TrEMBL
      Q542R1
      Conserved Domains (1) summary
      cl25352
      Location:32142
      EFh_PEF; The penta-EF hand (PEF) family
    6. XM_006504373.2XP_006504436.1  calcium-binding protein 8 isoform X4

      See identical proteins and their annotated locations for XP_006504436.1

      UniProtKB/Swiss-Prot
      Q9JJG7
      UniProtKB/TrEMBL
      Q542R1
      Related
      ENSMUSP00000106918.1, ENSMUST00000111287.7
      Conserved Domains (1) summary
      cl25352
      Location:32142
      EFh_PEF; The penta-EF hand (PEF) family
    7. XM_006504366.3XP_006504429.3  calcium-binding protein 8 isoform X1

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