Format

Send to:

Choose Destination
    • Showing Current items.

    Cplx1 complexin 1 [ Mus musculus (house mouse) ]

    Gene ID: 12889, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cplx1provided by MGI
    Official Full Name
    complexin 1provided by MGI
    Primary source
    MGI:MGI:104727
    See related
    Ensembl:ENSMUSG00000033615
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    921-S
    Expression
    Biased expression in cerebellum adult (RPKM 127.9), frontal lobe adult (RPKM 105.0) and 3 other tissues See more
    Orthologs

    Genomic context

    See Cplx1 in Genome Data Viewer
    Location:
    5; 5 F
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (108518554..108550027, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (108947573..108979046, complement)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene polycomb group ring finger 3 Neighboring gene ribosomal protein L34 pseudogene Neighboring gene cyclin G associated kinase Neighboring gene transmembrane protein 175 Neighboring gene diacylglycerol kinase, theta Neighboring gene iduronidase, alpha-L

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    SNARE binding ISO
    Inferred from Sequence Orthology
    more info
     
    neurotransmitter transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    syntaxin binding IEA
    Inferred from Electronic Annotation
    more info
     
    syntaxin-1 binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    Component Evidence Code Pubs
    SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    SNARE complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Schaffer collateral - CA1 synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Schaffer collateral - CA1 synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    calyx of Held IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    dendrite ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    postsynapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    postsynapse ISO
    Inferred from Sequence Orthology
    more info
     
    presynapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    presynapse ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    synapse ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    terminal bouton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    complexin-1
    Names
    CPX I
    complexin I
    synaphin-2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007756.3NP_031782.3  complexin-1

      See identical proteins and their annotated locations for NP_031782.3

      Status: VALIDATED

      Source sequence(s)
      AK159026, BY278933, BY594213
      Consensus CDS
      CCDS39206.1
      UniProtKB/Swiss-Prot
      P63040
      Related
      ENSMUSP00000038502.9, ENSMUST00000046892.9
      Conserved Domains (1) summary
      pfam05835
      Location:1133
      Synaphin; Synaphin protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      108518554..108550027 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center