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    Smad5 SMAD family member 5 [ Cavia porcellus (domestic guinea pig) ]

    Gene ID: 100717571, updated on 3-Apr-2024

    Summary

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    Gene symbol
    Smad5
    Gene description
    SMAD family member 5
    See related
    Ensembl:ENSCPOG00000005773
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cavia porcellus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae; Cavia
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    chromosome: Un
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current mCavPor4.1 (GCF_034190915.1) Unplaced Scaffold NW_026947502.1 (32765651..32822905)
    103 previous assembly Cavpor3.0 (GCF_000151735.1) Unplaced Scaffold NT_176402.1 (24665571..24718511)

    NW_026947502.1Genomic Context describing neighboring genes Neighboring gene Putative F-box/LRR-repeat protein 21 Neighboring gene leukocyte cell derived chemotaxin 2 Neighboring gene transforming growth factor beta induced Neighboring gene small integral membrane protein 32 Neighboring gene transient receptor potential cation channel subfamily C member 7

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables I-SMAD binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in BMP signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in SMAD protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in anatomical structure morphogenesis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in transforming growth factor beta receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of heteromeric SMAD protein complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mothers against decapentaplegic homolog 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_034190915.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference mCavPor4.1

    Genomic

    1. NW_026947502.1 Reference mCavPor4.1

      Range
      32765651..32822905
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003473268.5 → XP_003473316.1  mothers against decapentaplegic homolog 5

      See identical proteins and their annotated locations for XP_003473316.1

      UniProtKB/TrEMBL
      H0V696
      Related
      ENSCPOP00000005206.2
      Conserved Domains (2) summary
      cd10490
      Location:10 → 133
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9

    2. XM_063230925.1 → XP_063086995.1  mothers against decapentaplegic homolog 5

      UniProtKB/TrEMBL
      H0V696

    3. XM_013156212.3 → XP_013011666.1  mothers against decapentaplegic homolog 5

      See identical proteins and their annotated locations for XP_013011666.1

      UniProtKB/TrEMBL
      H0V696
      Conserved Domains (2) summary
      cd10490
      Location:10 → 133
      MH1_SMAD_1_5_9; N-terminal Mad Homology 1 (MH1) domain in SMAD1, SMAD5 and SMAD9 (also known as SMAD8)
      cd10497
      Location:265 → 465
      MH2_SMAD_1_5_9; C-terminal Mad Homology 2 (MH2) domain in SMAD1, SMAD5 and SMAD9
    Nucleotide Protein
    Heading Accession and Version

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