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    ARRB2 arrestin beta 2 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

    Gene ID: 100599882, updated on 10-Feb-2018

    Summary

    Gene symbol
    ARRB2
    Gene description
    arrestin beta 2
    See related
    Ensembl:ENSNLEG00000017374
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Nomascus leucogenys
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
    Orthologs

    Genomic context

    See ARRB2 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    102 current Nleu_3.0 (GCF_000146795.2) 19 NC_019834.1 (77001526..77012285, complement)

    Chromosome 19 - NC_019834.1Genomic Context describing neighboring genes Neighboring gene zinc finger MYND-type containing 15 Neighboring gene C-X-C motif chemokine ligand 16 Neighboring gene 40S ribosomal protein S12 pseudogene Neighboring gene proline, glutamate and leucine rich protein 1 Neighboring gene 60S ribosomal protein L12 pseudogene

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_019834.1 Chromosome 19 Reference Nleu_3.0

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Chemokine signaling pathway, organism-specific biosystem (from KEGG)
      Chemokine signaling pathway, organism-specific biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
    • Chemokine signaling pathway, conserved biosystem (from KEGG)
      Chemokine signaling pathway, conserved biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
    • Endocytosis, organism-specific biosystem (from KEGG)
      Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Endocytosis, conserved biosystem (from KEGG)
      Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Hedgehog signaling pathway, organism-specific biosystem (from KEGG)
      Hedgehog signaling pathway, organism-specific biosystemThe Hedgehog (Hh) signaling pathway has numerous roles in the control of cell proliferation, tissue patterning, stem cell maintenance and development. The primary cilium is an important center for tr...
    • Hedgehog signaling pathway, conserved biosystem (from KEGG)
      Hedgehog signaling pathway, conserved biosystemThe Hedgehog (Hh) signaling pathway has numerous roles in the control of cell proliferation, tissue patterning, stem cell maintenance and development. The primary cilium is an important center for tr...
    • MAPK signaling pathway, organism-specific biosystem (from KEGG)
      MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • MAPK signaling pathway, conserved biosystem (from KEGG)
      MAPK signaling pathway, conserved biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • Morphine addiction, organism-specific biosystem (from KEGG)
      Morphine addiction, organism-specific biosystemMorphine is an alkaloid from the plant extracts of opium poppy. Although morphine is highly effective for the treatment of pain, it is also known to be intensely addictive. We now know that the most ...
    • Morphine addiction, conserved biosystem (from KEGG)
      Morphine addiction, conserved biosystemMorphine is an alkaloid from the plant extracts of opium poppy. Although morphine is highly effective for the treatment of pain, it is also known to be intensely addictive. We now know that the most ...
    • Olfactory transduction, organism-specific biosystem (from KEGG)
      Olfactory transduction, organism-specific biosystemWithin the compact cilia of the olfactory receptor neurons (ORNs) a cascade of enzymatic activity transduces the binding of an odorant molecule to a receptor into an electrical signal that can be tra...
    • Olfactory transduction, conserved biosystem (from KEGG)
      Olfactory transduction, conserved biosystemWithin the compact cilia of the olfactory receptor neurons (ORNs) a cascade of enzymatic activity transduces the binding of an odorant molecule to a receptor into an electrical signal that can be tra...

    General gene information

    Markers

    Homology

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Nleu_3.0

    Genomic

    1. NC_019834.1 Reference Nleu_3.0

      Range
      77001526..77012285 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003277861.2XP_003277909.1  beta-arrestin-2 isoform X5

      See identical proteins and their annotated locations for XP_003277909.1

      Conserved Domains (2) summary
      smart01017
      Location:179334
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:19160
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    2. XM_004091548.2XP_004091596.1  beta-arrestin-2 isoform X4

      See identical proteins and their annotated locations for XP_004091596.1

      Related
      ENSNLEP00000045154.1, ENSNLET00000055793.1
      Conserved Domains (2) summary
      smart01017
      Location:179334
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      cl22903
      Location:19160
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    3. XM_004091547.2XP_004091595.1  beta-arrestin-2 isoform X6

      Conserved Domains (2) summary
      smart01017
      Location:194264
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:19175
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    4. XM_003277858.2XP_003277906.1  beta-arrestin-2 isoform X3

      See identical proteins and their annotated locations for XP_003277906.1

      UniProtKB/TrEMBL
      G1S6G2
      Conserved Domains (2) summary
      smart01017
      Location:194349
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:19175
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    5. XM_003277859.2XP_003277907.1  beta-arrestin-2 isoform X2

      See identical proteins and their annotated locations for XP_003277907.1

      Conserved Domains (2) summary
      smart01017
      Location:194349
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:19175
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
    6. XM_003277860.2XP_003277908.1  beta-arrestin-2 isoform X1

      See identical proteins and their annotated locations for XP_003277908.1

      Related
      ENSNLEP00000021101.3, ENSNLET00000022176.3
      Conserved Domains (2) summary
      smart01017
      Location:215370
      Arrestin_C; Arrestin (or S-antigen), C-terminal domain
      pfam00339
      Location:19196
      Arrestin_N; Arrestin (or S-antigen), N-terminal domain
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