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    LOC100597293 ras-related protein Rab-5C [ Nomascus leucogenys (northern white-cheeked gibbon) ]

    Gene ID: 100597293, updated on 19-Jan-2018

    Summary

    Gene symbol
    LOC100597293
    Gene description
    ras-related protein Rab-5C
    See related
    Ensembl:ENSNLEG00000011366
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Nomascus leucogenys
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
    Also known as
    KAT2A; RAB5C

    Genomic context

    See LOC100597293 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    26
    Annotation release Status Assembly Chr Location
    102 current Nleu_3.0 (GCF_000146795.2) Unplaced Scaffold NW_003501569.1 (1016623..1057301, complement)

    NW_003501569.1Genomic Context describing neighboring genes Neighboring gene NFKB inhibitor interacting Ras like 2 Neighboring gene zinc finger protein 385C Neighboring gene DExH-box helicase 58 Neighboring gene heat shock protein family B (small) member 9 Neighboring gene potassium voltage-gated channel subfamily H member 4 Neighboring gene hypocretin neuropeptide precursor

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NW_003501569.1 Unplaced Scaffold Reference Nleu_3.0

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Amoebiasis, organism-specific biosystem (from KEGG)
      Amoebiasis, organism-specific biosystemEntamoeba histolytica, an extracellular protozoan parasite is a human pathogen that invades the intestinal epithelium. Infection occurs on ingestion of contaminated water and food. The pathogenesis o...
    • Amoebiasis, conserved biosystem (from KEGG)
      Amoebiasis, conserved biosystemEntamoeba histolytica, an extracellular protozoan parasite is a human pathogen that invades the intestinal epithelium. Infection occurs on ingestion of contaminated water and food. The pathogenesis o...
    • Endocytosis, organism-specific biosystem (from KEGG)
      Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Endocytosis, conserved biosystem (from KEGG)
      Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Phagosome, organism-specific biosystem (from KEGG)
      Phagosome, organism-specific biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
    • Phagosome, conserved biosystem (from KEGG)
      Phagosome, conserved biosystemPhagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is...
    • Ras signaling pathway, organism-specific biosystem (from KEGG)
      Ras signaling pathway, organism-specific biosystemThe Ras proteins are GTPases that function as molecular switches for signaling pathways regulating cell proliferation, survival, growth, migration, differentiation or cytoskeletal dynamism. Ras prote...
    • Tuberculosis, organism-specific biosystem (from KEGG)
      Tuberculosis, organism-specific biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
    • Tuberculosis, conserved biosystem (from KEGG)
      Tuberculosis, conserved biosystemTuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent...
    • Vasopressin-regulated water reabsorption, organism-specific biosystem (from KEGG)
      Vasopressin-regulated water reabsorption, organism-specific biosystemIn the kidney, the antidiuretic hormone vasopressin (AVP) is a critical regulator of water homeostasis by controlling the water movement from lumen to the interstitium for water reabsorption and adju...
    • Vasopressin-regulated water reabsorption, conserved biosystem (from KEGG)
      Vasopressin-regulated water reabsorption, conserved biosystemIn the kidney, the antidiuretic hormone vasopressin (AVP) is a critical regulator of water homeostasis by controlling the water movement from lumen to the interstitium for water reabsorption and adju...

    General gene information

    Markers

    General protein information

    Preferred Names
    histone acetyltransferase KAT2A; ras-related protein Rab-5C
    Names
    K(lysine) acetyltransferase 2A
    RAB5C, member RAS oncogene family

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Nleu_3.0

    Genomic

    1. NW_003501569.1 Reference Nleu_3.0

      Range
      1016623..1057301 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003279457.3XP_003279505.2  histone acetyltransferase KAT2A isoform X1

      Conserved Domains (4) summary
      cd05509
      Location:631730
      Bromo_gcn5_like; Bromodomain; Gcn5_like subfamily. Gcn5p is a histone acetyltransferase (HAT) which mediates acetylation of histones at lysine residues; such acetylation is generally correlated with the activation of transcription. Bromodomains are 110 amino acid long ...
      COG5076
      Location:391731
      COG5076; Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription]
      pfam00583
      Location:454526
      Acetyltransf_1; Acetyltransferase (GNAT) family
      pfam06466
      Location:23234
      PCAF_N; PCAF (P300/CBP-associated factor) N-terminal domain
    2. XM_003279453.3XP_003279501.1  ras-related protein Rab-5C isoform X3

      See identical proteins and their annotated locations for XP_003279501.1

      UniProtKB/TrEMBL
      G1RKW8
      Conserved Domains (1) summary
      cd01860
      Location:21183
      Rab5_related; Rab-related GTPase family includes Rab5 and Rab22; regulates early endosome fusion
    3. XM_003279455.3XP_003279503.1  ras-related protein Rab-5C isoform X2

      Related
      ENSNLEP00000013875.2, ENSNLET00000014557.2
      Conserved Domains (2) summary
      cd01860
      Location:54216
      Rab5_related; Rab-related GTPase family includes Rab5 and Rab22; regulates early endosome fusion
      pfam00071
      Location:56217
      Ras; Ras family
    4. XM_003279454.3XP_003279502.1  ras-related protein Rab-5C isoform X3

      See identical proteins and their annotated locations for XP_003279502.1

      UniProtKB/TrEMBL
      G1RKW8
      Conserved Domains (1) summary
      cd01860
      Location:21183
      Rab5_related; Rab-related GTPase family includes Rab5 and Rab22; regulates early endosome fusion
    5. XM_004092705.2XP_004092753.1  ras-related protein Rab-5C isoform X3

      See identical proteins and their annotated locations for XP_004092753.1

      UniProtKB/TrEMBL
      G1RKW8
      Conserved Domains (1) summary
      cd01860
      Location:21183
      Rab5_related; Rab-related GTPase family includes Rab5 and Rab22; regulates early endosome fusion
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