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    MECOM MDS1 and EVI1 complex locus [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100343228, updated on 3-Apr-2017

    Summary

    Gene symbol
    MECOM
    Gene description
    MDS1 and EVI1 complex locus
    See related
    Ensembl:ENSOCUG00000010171
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs

    Genomic context

    See MECOM in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    102 current OryCun2.0 (GCF_000003625.3) 14 NC_013682.1 (63983704..64284375, complement)

    Chromosome 14 - NC_013682.1Genomic Context describing neighboring genes Neighboring gene multiple epidermal growth factor-like domains protein 6 Neighboring gene elongation factor 1-alpha 1 pseudogene Neighboring gene transfer RNA valine (anticodon AAC) Neighboring gene actin related protein T3

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_013682.1 Chromosome 14 Reference OryCun2.0 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Chronic myeloid leukemia, organism-specific biosystem (from KEGG)
      Chronic myeloid leukemia, organism-specific biosystemChronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of a pluripotent stem cell. The natural history of CML has a triphasic clinical course comprising of an initial chronic phase (C...
    • Chronic myeloid leukemia, conserved biosystem (from KEGG)
      Chronic myeloid leukemia, conserved biosystemChronic myeloid leukemia (CML) is a clonal myeloproliferative disorder of a pluripotent stem cell. The natural history of CML has a triphasic clinical course comprising of an initial chronic phase (C...
    • MAPK signaling pathway, organism-specific biosystem (from KEGG)
      MAPK signaling pathway, organism-specific biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • MAPK signaling pathway, conserved biosystem (from KEGG)
      MAPK signaling pathway, conserved biosystemThe mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in various cellular functions, including cell proliferation, differentiation and migration. Mammals e...
    • Pathways in cancer, organism-specific biosystem (from KEGG)
      Pathways in cancer, organism-specific biosystem
      Pathways in cancer

    General gene information

    Markers

    Homology

    General protein information

    Preferred Names
    MDS1 and EVI1 complex locus protein EVI1

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Oryctolagus cuniculus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference OryCun2.0 Primary Assembly

    Genomic

    1. NC_013682.1 Reference OryCun2.0 Primary Assembly

      Range
      63983704..64284375 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017346906.1XP_017202395.1  MDS1 and EVI1 complex locus protein EVI1 isoform X7

      Conserved Domains (6) summary
      PHA00733
      Location:817936
      PHA00733; hypothetical protein
      smart00317
      Location:52168
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      sd00017
      Location:886906
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:884906
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:898922
      zf-H2C2_2; Zinc-finger double domain
      pfam15909
      Location:323404
      zf-C2H2_8; C2H2-type zinc ribbon
    2. XM_017346905.1XP_017202394.1  MDS1 and EVI1 complex locus protein EVI1 isoform X6

      Conserved Domains (5) summary
      smart00317
      Location:52168
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      sd00017
      Location:895915
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:893915
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:907931
      zf-H2C2_2; Zinc-finger double domain
      pfam15909
      Location:323404
      zf-C2H2_8; C2H2-type zinc ribbon
    3. XM_017346904.1XP_017202393.1  MDS1 and EVI1 complex locus protein EVI1 isoform X5

      Conserved Domains (5) summary
      smart00317
      Location:52168
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      sd00017
      Location:896916
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:894916
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:908932
      zf-H2C2_2; Zinc-finger double domain
      pfam15909
      Location:324405
      zf-C2H2_8; C2H2-type zinc ribbon
    4. XM_008266458.2XP_008264680.1  MDS1 and EVI1 complex locus protein EVI1 isoform X9

      Conserved Domains (5) summary
      smart00317
      Location:2110
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      COG5048
      Location:203545
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:504524
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:502524
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:516540
      zf-H2C2_2; Zinc-finger double domain
    5. XM_017346907.1XP_017202396.1  MDS1 and EVI1 complex locus protein EVI1 isoform X8

    6. XM_008266451.2XP_008264673.1  MDS1 and EVI1 complex locus protein EVI1 isoform X1

      Conserved Domains (6) summary
      PHA00733
      Location:760879
      PHA00733; hypothetical protein
      smart00317
      Location:2110
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      sd00017
      Location:829849
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:827849
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:841865
      zf-H2C2_2; Zinc-finger double domain
      pfam15909
      Location:266347
      zf-C2H2_8; C2H2-type zinc ribbon
    7. XM_008266453.2XP_008264675.1  MDS1 and EVI1 complex locus protein EVI1 isoform X3

      See identical proteins and their annotated locations for XP_008264675.1

      Conserved Domains (4) summary
      sd00017
      Location:736756
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:734756
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:748772
      zf-H2C2_2; Zinc-finger double domain
      pfam15909
      Location:164245
      zf-C2H2_8; C2H2-type zinc ribbon
    8. XM_017346901.1XP_017202390.1  MDS1 and EVI1 complex locus protein EVI1 isoform X3

      Related
      ENSOCUP00000008768.2, ENSOCUT00000010173.3
      Conserved Domains (4) summary
      sd00017
      Location:736756
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:734756
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:748772
      zf-H2C2_2; Zinc-finger double domain
      pfam15909
      Location:164245
      zf-C2H2_8; C2H2-type zinc ribbon
    9. XM_017346902.1XP_017202391.1  MDS1 and EVI1 complex locus protein EVI1 isoform X3

      Conserved Domains (4) summary
      sd00017
      Location:736756
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:734756
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:748772
      zf-H2C2_2; Zinc-finger double domain
      pfam15909
      Location:164245
      zf-C2H2_8; C2H2-type zinc ribbon
    10. XM_008266452.2XP_008264674.1  MDS1 and EVI1 complex locus protein EVI1 isoform X2

      Conserved Domains (5) summary
      smart00317
      Location:772
      SET; SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain
      sd00017
      Location:800820
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:798820
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:812836
      zf-H2C2_2; Zinc-finger double domain
      pfam15909
      Location:228309
      zf-C2H2_8; C2H2-type zinc ribbon
    11. XM_017346903.1XP_017202392.1  MDS1 and EVI1 complex locus protein EVI1 isoform X4

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