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    PIAS3 protein inhibitor of activated STAT 3 [ Oryctolagus cuniculus (rabbit) ]

    Gene ID: 100341019, updated on 3-Apr-2017

    Summary

    Gene symbol
    PIAS3
    Gene description
    protein inhibitor of activated STAT 3
    See related
    Ensembl:ENSOCUG00000026198
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Oryctolagus cuniculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus
    Orthologs

    Genomic context

    See PIAS3 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    102 current OryCun2.0 (GCF_000003625.3) 13 NC_013681.1 (42870417..42877283)

    Chromosome 13 - NC_013681.1Genomic Context describing neighboring genes Neighboring gene integrin subunit alpha 10 Neighboring gene tubulin-specific chaperone A pseudogene Neighboring gene ankyrin repeat domain 35 Neighboring gene extensin-like Neighboring gene RNA polymerase III subunit C Neighboring gene ring finger protein 115 Neighboring gene 40S ribosomal protein S29-like

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_013681.1 Chromosome 13 Reference OryCun2.0 Primary Assembly

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Jak-STAT signaling pathway, organism-specific biosystem (from KEGG)
      Jak-STAT signaling pathway, organism-specific biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
    • Jak-STAT signaling pathway, conserved biosystem (from KEGG)
      Jak-STAT signaling pathway, conserved biosystemThe Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway is one of a handful of pleiotropic cascades used to transduce a multitude of signals for development and homeost...
    • Ubiquitin mediated proteolysis, organism-specific biosystem (from KEGG)
      Ubiquitin mediated proteolysis, organism-specific biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...
    • Ubiquitin mediated proteolysis, conserved biosystem (from KEGG)
      Ubiquitin mediated proteolysis, conserved biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...

    General protein information

    Preferred Names
    E3 SUMO-protein ligase PIAS3

    NCBI Reference Sequences (RefSeq)

    RefSeqs of Annotated Genomes: Oryctolagus cuniculus Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference OryCun2.0 Primary Assembly

    Genomic

    1. NC_013681.1 Reference OryCun2.0 Primary Assembly

      Range
      42870417..42877283
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008264544.2XP_008262766.1  E3 SUMO-protein ligase PIAS3 isoform X1

      Related
      ENSOCUP00000016713.1, ENSOCUT00000024594.1
      Conserved Domains (3) summary
      smart00513
      Location:1136
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam02891
      Location:323371
      zf-MIZ; MIZ/SP-RING zinc finger
      pfam14324
      Location:126263
      PINIT; PINIT domain
    2. XM_008264548.2XP_008262770.1  E3 SUMO-protein ligase PIAS3 isoform X2

      Conserved Domains (3) summary
      smart00513
      Location:1136
      SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation
      pfam02891
      Location:323371
      zf-MIZ; MIZ/SP-RING zinc finger
      pfam14324
      Location:126263
      PINIT; PINIT domain
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