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    CCL8 chemokine (C-C motif) ligand 8 [ Sus scrofa (pig) ]

    Gene ID: 100302703, updated on 8-Dec-2018

    Summary

    Gene symbol
    CCL8
    Gene description
    chemokine (C-C motif) ligand 8
    See related
    Ensembl:ENSSSCG00000040648
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in lung (RPKM 5.8), spleen (RPKM 3.3) and 8 other tissues See more

    Genomic context

    See CCL8 in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 12 NC_010454.4 (40740468..40741970, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 12 NC_010454.3 (42456902..42458404)

    Chromosome 12 - NC_010454.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106505468 Neighboring gene C-C motif chemokine ligand 1 Neighboring gene chemokine (C-C motif) ligand 11 Neighboring gene chemokine (C-C motif) ligand 2

    Genomic regions, transcripts, and products

    Bibliography

    Related articles in PubMed

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    • Chemokine signaling pathway, organism-specific biosystem (from KEGG)
      Chemokine signaling pathway, organism-specific biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
    • Chemokine signaling pathway, conserved biosystem (from KEGG)
      Chemokine signaling pathway, conserved biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
    • Cytokine-cytokine receptor interaction, organism-specific biosystem (from KEGG)
      Cytokine-cytokine receptor interaction, organism-specific biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
    • Cytokine-cytokine receptor interaction, conserved biosystem (from KEGG)
      Cytokine-cytokine receptor interaction, conserved biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...

    General gene information

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    heparin binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    regulation of signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    C-C motif chemokine 8
    Names
    MCP-2
    chemokine ligand 8
    monocyte chemoattractant protein 2
    monocyte chemotactic protein 2
    small-inducible cytokine A8

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164515.1NP_001157987.1  C-C motif chemokine 8 precursor

      See identical proteins and their annotated locations for NP_001157987.1

      Status: PROVISIONAL

      Source sequence(s)
      GQ338308
      UniProtKB/TrEMBL
      C7F842
      Related
      ENSSSCP00000032773.1, ENSSSCT00000044167.1
      Conserved Domains (1) summary
      pfam00048
      Location:3388
      IL8; Small cytokines (intecrine/chemokine), interleukin-8 like

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010454.4 Reference Sscrofa11.1 Primary Assembly

      Range
      40740468..40741970 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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