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    HEY2 hes related family bHLH transcription factor with YRPW motif 2 [ Sus scrofa (pig) ]

    Gene ID: 100152404, updated on 2-Oct-2018

    Summary

    Gene symbol
    HEY2
    Gene description
    hes related family bHLH transcription factor with YRPW motif 2
    See related
    Ensembl:ENSSSCG00000004223
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; Sus
    Expression
    Biased expression in ovary (RPKM 19.3), heart (RPKM 19.0) and 2 other tissues See more
    Orthologs

    Genomic context

    See HEY2 in Genome Data Viewer
    Location:
    1; 1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 1 NC_010443.5 (37219887..37231321, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (40989466..41000901, complement)

    Chromosome 1 - NC_010443.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110260188 Neighboring gene transfer RNA glutamic acid (anticodon CUC) Neighboring gene uncharacterized LOC110260189 Neighboring gene uncharacterized protein C12orf45 homolog pseudogene

    Genomic regions, transcripts, and products

    Pathways from BioSystems

    • Breast cancer, organism-specific biosystem (from KEGG)
      Breast cancer, organism-specific biosystemBreast cancer is the leading cause of cancer death among women worldwide. The vast majority of breast cancers are carcinomas that originate from cells lining the milk-forming ducts of the mammary gla...
    • Breast cancer, conserved biosystem (from KEGG)
      Breast cancer, conserved biosystemBreast cancer is the leading cause of cancer death among women worldwide. The vast majority of breast cancers are carcinomas that originate from cells lining the milk-forming ducts of the mammary gla...

    General protein information

    Preferred Names
    hairy/enhancer-of-split related with YRPW motif protein 2
    Names
    hairy/enhancer-of-split related with YRPW motif 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001243329.1NP_001230258.1  hairy/enhancer-of-split related with YRPW motif protein 2

      Status: VALIDATED

      Source sequence(s)
      AK347619, BP149699, BP172681
      UniProtKB/TrEMBL
      F1S2V4
      Related
      ENSSSCP00000004561.2, ENSSSCT00000004668.3
      Conserved Domains (2) summary
      smart00511
      Location:119165
      ORANGE; Orange domain
      cd00083
      Location:49105
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010443.5 Reference Sscrofa11.1 Primary Assembly

      Range
      37219887..37231321 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_013992576.2XP_013848030.1  hairy/enhancer-of-split related with YRPW motif protein 2 isoform X1

      Conserved Domains (2) summary
      smart00511
      Location:92138
      ORANGE; Orange domain
      cd00083
      Location:2278
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    2. XM_021086293.1XP_020941952.1  hairy/enhancer-of-split related with YRPW motif protein 2 isoform X2

      Conserved Domains (2) summary
      smart00511
      Location:73119
      ORANGE; Orange domain
      cd00083
      Location:359
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
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