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    rluA dual specificity 23S rRNA pseudouridine(746), tRNA pseudouridine(32) synthase, SAM-dependent [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946262, updated on 25-May-2017
    Gene symbol
    rluA
    Gene description
    dual specificity 23S rRNA pseudouridine(746), tRNA pseudouridine(32) synthase, SAM-dependent
    Primary source
    EcoGene:EG12609
    Locus tag
    b0058
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0059; JW0057; yabO
    Summary
    RluA is the pseudouridine synthase that catalyzes formation of pseudouridine at position 746 in 23S rRNA and at position 32 in tRNAPhe . [More information is available at EcoCyc: EG12609].
    Sequence:
    NC_000913.3 (59687..60346, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene membrane-anchored DnaK co-chaperone, DNA-binding protein Neighboring gene pseudo Neighboring gene RNA polymerase remodeling/recycling factor ATPase; RNA polymerase-associated, ATP-dependent RNA translocase Neighboring gene DNA polymerase II

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    pseudouridine synthase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    pseudouridine synthase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    RNA modification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enzyme-directed rRNA pseudouridine synthesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    pseudouridine synthesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    rRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    rRNA pseudouridine synthesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    tRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    tRNA pseudouridine synthesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Names
    dual specificity 23S rRNA pseudouridine(746), tRNA pseudouridine(32) synthase, SAM-dependent
    NP_414600.1

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      59687..60346 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414600.1 dual specificity 23S rRNA pseudouridine(746), tRNA pseudouridine(32) synthase, SAM-dependent [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414600.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P0AA37
      Conserved Domains (2) summary
      COG0564
      Location:9219
      RluA; Pseudouridylate synthase, 23S rRNA- or tRNA-specific [Translation, ribosomal structure and biogenesis]
      PRK10158
      Location:1219
      PRK10158; 23S rRNA/tRNA pseudouridine synthase A; Provisional
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