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    Gpbar1 G protein-coupled bile acid receptor 1 [ Mus musculus (house mouse) ]

    Gene ID: 227289, updated on 20-Dec-2016
    Official Symbol
    Gpbar1provided by MGI
    Official Full Name
    G protein-coupled bile acid receptor 1provided by MGI
    Primary source
    MGI:MGI:2653863
    See related
    Ensembl:ENSMUSG00000064272 Vega:OTTMUSG00000047666
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BG37; GPCR; TGR5; M-BAR; GPR131
    Orthologs
    Location:
    1 C3; 1 38.53 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (74278600..74279589)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (74325174..74326163)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 31691 Neighboring gene actin related protein 2/3 complex, subunit 2 Neighboring gene predicted gene 28364 Neighboring gene angio-associated migratory protein Neighboring gene transmembrane BAX inhibitor motif containing 1 Neighboring gene paroxysmal nonkinesiogenic dyskinesia

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G-protein coupled receptor activity ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    bile acid receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    signal transducer activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    G-protein coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of bicellular tight junction assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    G-protein coupled bile acid receptor 1
    Names
    G protein-coupled receptor TGR5
    membrane bile acid receptor
    membrane-type receptor for bile acids

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_174985.1NP_778150.1  G-protein coupled bile acid receptor 1

      See identical proteins and their annotated locations for NP_778150.1

      Status: PROVISIONAL

      Source sequence(s)
      AB089308
      Consensus CDS
      CCDS15042.1
      UniProtKB/Swiss-Prot
      Q80SS6
      UniProtKB/TrEMBL
      Q14AA9
      Related
      ENSMUSP00000077135, OTTMUSP00000067261, ENSMUST00000077985, OTTMUST00000122846
      Conserved Domains (1) summary
      pfam00001
      Location:108249
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      74278600..74279589
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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