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    Myf5 myogenic factor 5 [ Mus musculus (house mouse) ]

    Gene ID: 17877, updated on 12-Mar-2017
    Official Symbol
    Myf5provided by MGI
    Official Full Name
    myogenic factor 5provided by MGI
    Primary source
    MGI:MGI:97252
    See related
    Ensembl:ENSMUSG00000000435
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Myf-5; bHLHc2; B130010J22Rik
    Orthologs
    Location:
    10 D1; 10 55.95 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (107482908..107486927, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (106919964..106923190, complement)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 29674 Neighboring gene lin-7 homolog A (C. elegans) Neighboring gene predicted gene, 36177 Neighboring gene myogenic factor 6 Neighboring gene protein tyrosine phosphatase, receptor type, Q

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    camera-type eye development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cartilage condensation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    embryonic skeletal system morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    extracellular matrix organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    muscle organ development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    muscle organ development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    muscle organ morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    muscle tissue morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    muscle tissue morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ossification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of myoblast differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of myoblast fusion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of skeletal muscle fiber development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    positive regulation of transcription from RNA polymerase II promoter IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription from RNA polymerase II promoter IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of cell-matrix adhesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    skeletal muscle cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    skeletal muscle tissue development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    skeletal muscle tissue development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    somitogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus TAS
    Traceable Author Statement
    more info
    PubMed 
    Preferred Names
    myogenic factor 5
    Names
    myogenic regulatory factor MYF-5

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_008656.5NP_032682.1  myogenic factor 5

      See identical proteins and their annotated locations for NP_032682.1

      Status: VALIDATED

      Source sequence(s)
      AK044894, AK083402
      Consensus CDS
      CCDS24161.1
      UniProtKB/Swiss-Prot
      P24699
      UniProtKB/TrEMBL
      A2RSK4
      Related
      ENSMUSP00000000445, ENSMUST00000000445
      Conserved Domains (3) summary
      smart00520
      Location:188
      BASIC; Basic domain in HLH proteins of MYOD family
      pfam00010
      Location:84135
      HLH; Helix-loop-helix DNA-binding domain
      pfam12232
      Location:143214
      Myf5; Myogenic determination factor 5

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      107482908..107486927 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513319.2XP_006513382.1  myogenic factor 5 isoform X1

      See identical proteins and their annotated locations for XP_006513382.1

      UniProtKB/Swiss-Prot
      P24699
      UniProtKB/TrEMBL
      A2RSK4
      Conserved Domains (3) summary
      smart00520
      Location:188
      BASIC; Basic domain in HLH proteins of MYOD family
      pfam00010
      Location:84135
      HLH; Helix-loop-helix DNA-binding domain
      pfam12232
      Location:143214
      Myf5; Myogenic determination factor 5
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