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    OXA1 membrane insertase OXA1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 856898, updated on 5-Nov-2017
    Gene symbol
    OXA1
    Gene description
    membrane insertase OXA1
    Primary source
    SGD:S000000956
    Locus tag
    YER154W
    Gene type
    protein coding
    RNA name
    membrane insertase OXA1
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288c)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Location:
    chromosome: V
    Exon count:
    1
    Sequence:
    Chromosome: V; NC_001137.3 (475020..476228)

    Chromosome V - NC_001137.3Genomic Context describing neighboring genes Neighboring gene 2-aminoadipate transaminase Neighboring gene Pet122p Neighboring gene Bem2p Neighboring gene hypothetical protein

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    • Protein export, organism-specific biosystem (from KEGG)
      Protein export, organism-specific biosystemThe protein export is the active transport of proteins from the cytoplasm to the exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria. The sec dependent pathway is the ge...
    • Protein export, conserved biosystem (from KEGG)
      Protein export, conserved biosystemThe protein export is the active transport of proteins from the cytoplasm to the exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria. The sec dependent pathway is the ge...
    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    ion channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane insertase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitochondrial ribosome binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial crista IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial inner boundary membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with mitochondrial large ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    Names
    membrane insertase OXA1
    NP_011081.1
    • Mitochondrial inner membrane insertase; mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane; also has a role in insertion of carrier proteins into the inner membrane; acts as a voltage-gated ion channel, activated by substrate peptides; interacts with mitochondrial ribosomes; conserved from bacteria to animals

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001137.3 Reference assembly

      Range
      475020..476228
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179044.1NP_011081.1  TPA: membrane insertase OXA1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_011081.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P39952
      Conserved Domains (1) summary
      COG0706
      Location:16334
      YidC; Membrane protein insertase Oxa1/YidC/SpoIIIJ, required for the localization of integral membrane proteins [Cell wall/membrane/envelope biogenesis]
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