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    amiB N-acetylmuramoyl-l-alanine amidase II [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948683, updated on 25-May-2017
    Gene symbol
    amiB
    Gene description
    N-acetylmuramoyl-l-alanine amidase II
    Primary source
    EcoGene:EG11363
    Locus tag
    b4169
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
    Also known as
    ECK4165; JW4127; yjeD
    Summary
    First 22 aa are predicted to be a type I signal peptide. [More information is available at EcoGene: EG11363]. Escherichia coli contains three N-acetylmuramyl-L-alanine amidases named AmiA, B, and C involved in cell division by splitting the murein septum. [More information is available at EcoCyc: EG11363].
    Sequence:
    NC_000913.3 (4396065..4397402)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene epoxyqueuosine reductase, cobalamine-stimulated; queosine biosynthesis Neighboring gene bifunctional NAD(P)H-hydrate repair enzyme; C-terminal domain ADP-dependent (S)-NAD(P)H-hydrate dehydratase and N-terminal domain NAD(P)H-hydrate epimerase Neighboring gene tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; ADP binding protein Neighboring gene methyl-directed mismatch repair protein Neighboring gene delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase Neighboring gene global sRNA chaperone; HF-I, host factor for RNA phage Q beta replication

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    N-acetylmuramoyl-L-alanine amidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    FtsZ-dependent cytokinesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell division IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    outer membrane-bounded periplasmic space IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    outer membrane-bounded periplasmic space RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    Names
    N-acetylmuramoyl-l-alanine amidase II
    NP_418590.1
    • N-acetylmuramoyl-l-alanine amidase II; a murein hydrolase

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4396065..4397402
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418590.1 N-acetylmuramoyl-l-alanine amidase II [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418590.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P26365
      Conserved Domains (3) summary
      cd02696
      Location:193412
      MurNAc-LAA; N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino ...
      PRK10431
      Location:1445
      PRK10431; N-acetylmuramoyl-l-alanine amidase II; Provisional
      pfam11741
      Location:28123
      AMIN; AMIN domain
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