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    Rnaseh2b ribonuclease H2, subunit B [ Mus musculus (house mouse) ]

    Gene ID: 67153, updated on 25-May-2017
    Official Symbol
    Rnaseh2bprovided by MGI
    Official Full Name
    ribonuclease H2, subunit Bprovided by MGI
    Primary source
    MGI:MGI:1914403
    See related
    Ensembl:ENSMUSG00000021932 Vega:OTTMUSG00000019771
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dleu8; 1110019N06Rik; 2610207P08Rik
    Orthologs
    Location:
    14; 14 D1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (62332105..62372992)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (62950942..62991829)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene deleted in lymphocytic leukemia, 7 Neighboring gene predicted gene, 41173 Neighboring gene guanylate cyclase 1, soluble, beta 2 Neighboring gene predicted gene, 46457 Neighboring gene predicted gene, 35468

    • DNA replication, organism-specific biosystem (from KEGG)
      DNA replication, organism-specific biosystemA complex network of interacting proteins and enzymes is required for DNA replication. Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (D...
    • DNA replication, conserved biosystem (from KEGG)
      DNA replication, conserved biosystemA complex network of interacting proteins and enzymes is required for DNA replication. Generally, DNA replication follows a multistep enzymatic pathway. At the DNA replication fork, a DNA helicase (D...

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA-DNA hybrid ribonuclease activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    RNA catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of fibroblast proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of DNA damage checkpoint IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of G2/M transition of mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ribonucleotide metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    ribonuclease H2 complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ribonuclease H2 complex ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    ribonuclease H2 subunit B
    Names
    RNase H2 subunit B
    deleted in lymphocytic leukemia 8 homolog
    ribonuclease HI subunit B

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026001.2NP_080277.1  ribonuclease H2 subunit B

      See identical proteins and their annotated locations for NP_080277.1

      Status: PROVISIONAL

      Source sequence(s)
      AK082752
      Consensus CDS
      CCDS27189.1
      UniProtKB/Swiss-Prot
      Q80ZV0
      Related
      ENSMUSP00000022499.6, OTTMUSP00000021344, ENSMUST00000022499.12, OTTMUST00000047290
      Conserved Domains (1) summary
      cd09270
      Location:16299
      RNase_H2-B; Ribonuclease H2-B is a subunit of the eukaryotic RNase H complex which cleaves RNA-DNA hybrids

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      62332105..62372992
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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