Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    P2ry1 purinergic receptor P2Y, G-protein coupled 1 [ Mus musculus (house mouse) ]

    Gene ID: 18441, updated on 17-Sep-2016
    Official Symbol
    P2ry1provided by MGI
    Official Full Name
    purinergic receptor P2Y, G-protein coupled 1provided by MGI
    Primary source
    MGI:MGI:105049
    See related
    Ensembl:ENSMUSG00000027765 Vega:OTTMUSG00000051935
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P2Y1
    Orthologs
    Location:
    3; 3 D
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (61002785..61008982)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (60806717..60812901)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 37035 Neighboring gene predicted gene, 38326 Neighboring gene ubiquitin-conjugating enzyme E2 variant 1 pseudogene Neighboring gene splicing factor, arginine/serine-rich 13A-like Neighboring gene RAP2B, member of RAS oncogene family

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    A1 adenosine receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    ADP binding ISO
    Inferred from Sequence Orthology
    more info
     
    ADP-activated adenosine receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    ATP binding ISO
    Inferred from Sequence Orthology
    more info
     
    ATP-activated adenosine receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    G-protein coupled purinergic nucleotide receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    G-protein coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    scaffold protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    signal transducer activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    G-protein coupled purinergic nucleotide receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    G-protein coupled receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    adenosine receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to organic cyclic compound IDA
    Inferred from Direct Assay
    more info
    PubMed 
    eating behavior ISO
    Inferred from Sequence Orthology
    more info
     
    glial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of binding ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of norepinephrine secretion ISO
    Inferred from Sequence Orthology
    more info
     
    phospholipase C-activating G-protein coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    platelet activation IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of ERK1 and ERK2 cascade ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cytosolic calcium ion concentration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of hormone secretion ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of inositol trisphosphate biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of ion transport IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    positive regulation of ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of penile erection ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    protein localization to plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of vasodilation ISO
    Inferred from Sequence Orthology
    more info
     
    relaxation of muscle IEA
    Inferred from Electronic Annotation
    more info
     
    response to mechanical stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    sensory perception of pain ISO
    Inferred from Sequence Orthology
    more info
     
    signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    signal transduction involved in regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    basolateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    cell body ISO
    Inferred from Sequence Orthology
    more info
     
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    colocalizes_with mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    postsynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Preferred Names
    P2Y purinoceptor 1
    Names
    ATP receptor
    P2Y1 receptor

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001282016.1NP_001268945.1  P2Y purinoceptor 1

      See identical proteins and their annotated locations for NP_001268945.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK030759, AK033660, BY780693
      Consensus CDS
      CCDS17377.1
      UniProtKB/Swiss-Prot
      P49650
      UniProtKB/TrEMBL
      Q544J5, Q8BMJ5
      Related
      ENSMUSP00000142006, OTTMUSP00000070028, ENSMUST00000193201, OTTMUST00000130724
      Conserved Domains (1) summary
      pfam00001
      Location:68324
      7tm_1; 7 transmembrane receptor (rhodopsin family)
    2. NM_008772.5NP_032798.1  P2Y purinoceptor 1

      See identical proteins and their annotated locations for NP_032798.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK030759, AK033660, AK036611, BY780693
      Consensus CDS
      CCDS17377.1
      UniProtKB/Swiss-Prot
      P49650
      UniProtKB/TrEMBL
      Q544J5, Q8BMJ5
      Related
      ENSMUSP00000029331, OTTMUSP00000070027, ENSMUST00000029331, OTTMUST00000130723
      Conserved Domains (1) summary
      pfam00001
      Location:68324
      7tm_1; 7 transmembrane receptor (rhodopsin family)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      61002785..61008982
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center