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    Cd36 CD36 molecule [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29184, updated on 26-Nov-2016
    Official Symbol
    Cd36provided by RGD
    Official Full Name
    CD36 moleculeprovided by RGD
    Primary source
    RGD:2301
    See related
    Ensembl:ENSRNOG00000040108
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Fat; RGD1562323
    Summary
    fatty acid translocase; involved in long-chain fatty acid (LCFA) transport; important in fatty acid metabolism and insulin function [RGD, Feb 2006]
    Annotation information
    Annotation category: partial on reference assembly
    Location:
    4q11
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (14150309..14191498)
    104 previous assembly Rnor_5.0 (GCF_000001895.4) 4 NC_005103.3 (14125297..14166434)

    Chromosome 4 - NC_005103.4Genomic Context describing neighboring genes Neighboring gene similar to fatty acid translocase/CD36 Neighboring gene MLV-related proviral Env polyprotein-like Neighboring gene uncharacterized LOC108350653 Neighboring gene platelet glycoprotein 4-like

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Markers

    Homology

    Clone Names

    • MGC91634, MGC108510

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    high-density lipoprotein particle binding ISO
    Inferred from Sequence Orthology
    more info
     
    lipid binding ISO
    Inferred from Sequence Orthology
    more info
     
    lipoprotein particle binding ISO
    Inferred from Sequence Orthology
    more info
     
    lipoteichoic acid receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    low-density lipoprotein particle binding ISO
    Inferred from Sequence Orthology
    more info
     
    low-density lipoprotein receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    oleic acid binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    thrombospondin receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transforming growth factor beta binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    amyloid fibril formation ISO
    Inferred from Sequence Orthology
    more info
     
    amyloid fibril formation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    apoptotic cell clearance ISO
    Inferred from Sequence Orthology
    more info
     
    cGMP-mediated signaling ISO
    Inferred from Sequence Orthology
    more info
     
    cell surface receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    cell surface receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    cell-cell adhesion via plasma-membrane adhesion molecules IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cellular response to bacterial lipopeptide ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to diacyl bacterial lipopeptide ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to diacyl bacterial lipopeptide ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cellular response to hydroperoxide ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to insulin stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    cellular response to lipopolysaccharide ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to lipoteichoic acid ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to low-density lipoprotein particle stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    cellular response to low-density lipoprotein particle stimulus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cholesterol import ISO
    Inferred from Sequence Orthology
    more info
     
    cholesterol import ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    cholesterol transport ISO
    Inferred from Sequence Orthology
    more info
     
    defense response to Gram-positive bacterium ISO
    Inferred from Sequence Orthology
    more info
     
    digestive tract development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    eating behavior IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fatty acid metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    fatty acid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fatty acid oxidation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    fatty acid transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    fatty acid transport IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    fatty acid transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glucose homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    immune response IEA
    Inferred from Electronic Annotation
    more info
     
    interleukin-1 beta secretion ISO
    Inferred from Sequence Orthology
    more info
     
    interleukin-1 beta secretion ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    intestinal absorption ISO
    Inferred from Sequence Orthology
    more info
     
    intestinal absorption ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    intestinal cholesterol absorption ISO
    Inferred from Sequence Orthology
    more info
     
    intestinal cholesterol absorption ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    lipid storage ISO
    Inferred from Sequence Orthology
    more info
     
    lipoprotein transport ISO
    Inferred from Sequence Orthology
    more info
     
    long-chain fatty acid import ISO
    Inferred from Sequence Orthology
    more info
     
    long-chain fatty acid import ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    long-chain fatty acid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    long-chain fatty acid transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    low-density lipoprotein particle clearance ISO
    Inferred from Sequence Orthology
    more info
     
    low-density lipoprotein particle mediated signaling ISO
    Inferred from Sequence Orthology
    more info
     
    maternal placenta development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    negative regulation of angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of growth of symbiont in host ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of systemic arterial blood pressure IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription factor import into nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    nitric oxide mediated signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    phagocytosis, recognition ISO
    Inferred from Sequence Orthology
    more info
     
    plasma lipoprotein particle clearance ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of ERK1 and ERK2 cascade ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of MAPK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of NLRP3 inflammasome complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of NLRP3 inflammasome complex assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of blood coagulation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of blood microparticle formation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell-matrix adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cholesterol storage ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cytokine secretion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cytosolic calcium ion concentration ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cytosolic calcium ion concentration ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    positive regulation of interleukin-12 production ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of interleukin-6 production ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of macrophage cytokine production ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of macrophage derived foam cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of peptidyl-tyrosine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of phagocytosis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of phagocytosis, engulfment ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of reactive oxygen species metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of triglyceride metabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of tumor necrosis factor production ISO
    Inferred from Sequence Orthology
    more info
     
    receptor internalization ISO
    Inferred from Sequence Orthology
    more info
     
    receptor internalization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    regulation of energy homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of energy homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of removal of superoxide radicals ISO
    Inferred from Sequence Orthology
    more info
     
    response to activity IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to drug IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to estradiol IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to fatty acid IDA
    Inferred from Direct Assay
    more info
    PubMed 
    response to fatty acid IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to fatty acid ISO
    Inferred from Sequence Orthology
    more info
     
    response to growth hormone IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to linoleic acid ISO
    Inferred from Sequence Orthology
    more info
     
    response to linoleic acid ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    response to lipid IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to lipid ISO
    Inferred from Sequence Orthology
    more info
     
    response to mechanical stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    response to nutrient IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    response to stilbenoid ISO
    Inferred from Sequence Orthology
    more info
     
    sensory perception of taste ISO
    Inferred from Sequence Orthology
    more info
     
    sensory perception of taste ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    triglyceride metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    triglyceride transport ISO
    Inferred from Sequence Orthology
    more info
     
    triglyceride transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    Golgi apparatus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    apical part of cell IDA
    Inferred from Direct Assay
    more info
    PubMed 
    apical part of cell ISO
    Inferred from Sequence Orthology
    more info
     
    apical plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    brush border membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    brush border membrane ISO
    Inferred from Sequence Orthology
    more info
     
    caveola IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    external side of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    extracellular space ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    intracellular IDA
    Inferred from Direct Assay
    more info
    PubMed 
    intracellular membrane-bounded organelle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    membrane raft ISO
    Inferred from Sequence Orthology
    more info
     
    mitochondrion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    sarcolemma IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Preferred Names
    platelet glycoprotein 4
    Names
    CD36 antigen (collagen type I receptor, thrombospondin receptor)
    CD36 molecule (thrombospondin receptor)
    Cd36 antigen-like
    GPIIIB
    GPIV
    PAS IV
    PAS-4
    adipocyte membrane protein
    collagen type I receptor thrombospondin receptor
    fatty acid translocase
    fatty acid transport protein
    glycoprotein IIIb
    platelet glycoprotein IV

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031561.2NP_113749.2  platelet glycoprotein 4

      See identical proteins and their annotated locations for NP_113749.2

      Status: PROVISIONAL

      Source sequence(s)
      BC072543
      UniProtKB/TrEMBL
      Q6IMX5
      Related
      ENSRNOP00000069273, ENSRNOT00000091249
      Conserved Domains (1) summary
      pfam01130
      Location:16461
      CD36; CD36 family

    RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Rnor_6.0 Primary Assembly

    Genomic

    1. NC_005103.4 Reference Rnor_6.0 Primary Assembly

      Range
      14150309..14191498
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Rn_Celera

    Genomic

    1. AC_000072.1 Alternate Rn_Celera

      Range
      12880238..12941086
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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