Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 [ Mus musculus (house mouse) ]

    Gene ID: 15490, updated on 5-Nov-2017
    Official Symbol
    Hsd17b7provided by MGI
    Official Full Name
    hydroxysteroid (17-beta) dehydrogenase 7provided by MGI
    Primary source
    MGI:MGI:1330808
    See related
    Ensembl:ENSMUSG00000026675 Vega:OTTMUSG00000020778
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ERG27; AI266814
    Orthologs
    Location:
    1; 1 H3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (169949535..169969240, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (171879668..171899336, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 39699 Neighboring gene coiled-coil domain containing 190 Neighboring gene RIKEN cDNA 3110045C21 gene Neighboring gene discoidin domain receptor family, member 2 Neighboring gene UDP-N-acetylglucosamine pyrophosphorylase 1

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    3-keto sterol reductase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    estradiol 17-beta-dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    prolactin receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    cholesterol biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    steroid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    3-keto-steroid reductase
    Names
    17-beta-HSD 7
    17-beta-hydroxysteroid dehydrogenase 7
    estradiol 17-beta-dehydrogenase 7
    NP_034606.3
    XP_006496730.1
    XP_011237060.1
    XP_017172597.1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010476.3NP_034606.3  3-keto-steroid reductase

      See identical proteins and their annotated locations for NP_034606.3

      Status: VALIDATED

      Source sequence(s)
      AK050211, BB767054, BY228199
      Consensus CDS
      CCDS35766.1
      UniProtKB/Swiss-Prot
      O88736
      Related
      ENSMUSP00000027989.6, OTTMUSP00000022717, ENSMUST00000027989.12, OTTMUST00000049128
      Conserved Domains (2) summary
      cd08941
      Location:2280
      3KS_SDR_c; 3-keto steroid reductase, classical (c) SDRs
      COG1028
      Location:1305
      FabG; NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism, General function prediction only]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      169949535..169969240 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496667.2XP_006496730.1  3-keto-steroid reductase isoform X3

      Conserved Domains (2) summary
      COG1028
      Location:1286
      FabG; NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism, General function prediction only]
      cl21454
      Location:2261
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    2. XM_017317108.1XP_017172597.1  3-keto-steroid reductase isoform X2

    3. XM_011238758.1XP_011237060.1  3-keto-steroid reductase isoform X1

      Related
      ENSMUSP00000106985.3, OTTMUSP00000022718, ENSMUST00000111353.3, OTTMUST00000049129
      Conserved Domains (2) summary
      cd08941
      Location:2280
      3KS_SDR_c; 3-keto steroid reductase, classical (c) SDRs
      COG1028
      Location:1271
      FabG; NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism, General function prediction only]
    Support Center