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    US8 type 1 membrane protein; contains a signal peptide; complexed with envelope glycoprotein I to form an Fc-receptor; involved in cell-to-cell spread [ Human herpesvirus 1 (Herpes simplex virus type 1) ]

    Gene ID: 2703448, updated on 28-Jan-2017
    Gene symbol
    US8
    Gene description
    type 1 membrane protein; contains a signal peptide; complexed with envelope glycoprotein I to form an Fc-receptor; involved in cell-to-cell spread
    Locus tag
    HHV1gp00p07
    Gene type
    protein coding
    RNA name
    envelope glycoprotein E
    RefSeq status
    PROVISIONAL
    Organism
    Human herpesvirus 1 (strain: 17, acronym: HHV-1, acronym: HSV-1, gb-synonym: Herpes simplex virus 1, other: collected prior to 1972)
    Lineage
    Viruses; dsDNA viruses, no RNA stage; Herpesvirales; Herpesviridae; Alphaherpesvirinae; Simplexvirus
    Sequence:
    NC_001806.2 (141143..143697)

    NC_001806.2Genomic Context describing neighboring genes Neighboring gene tegument protein; phosphorylates nuclear egress lamina protein; mediates phosphorylation of HDAC1 and HDAC2 and other cellular and viral proteins; involved in protein phosphorylation; involved in apoptosis; involved in nuclear egress Neighboring gene type 1 membrane protein; contains a signal peptide; involved in cell-to-cell spread Neighboring gene type 1 membrane protein; contains a signal peptide Neighboring gene type 1 membrane protein; contains a signal peptide; binds cell surface receptors; involved in cell attachment Neighboring gene type 1 membrane protein; contains a signal peptide; complexed with envelope glycoprotein E to form an Fc-receptor; involved in cell-to-cell spread Neighboring gene type 2 membrane protein Neighboring gene type 2 membrane protein; tegument-associated; localizes envelope proteins; involved in axonal transport Neighboring gene virion protein US10 Neighboring gene dsRNA-binding protein; antagonizes PKR; inhibits stress-induced translational arrest; involved in translational regulation Neighboring gene inhibits antigen presentation; involved in immune regulation Neighboring gene involved in gene regulation

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    regulatory

    • Loc: 141143-141148 regulatory_class = TATA_box
    • Loc: 143223-143228 regulatory_class = TATA_box
    • Loc: 143672-143677 regulatory_class = polyA_signal_sequence
    Preferred Names
    type 1 membrane protein; contains a signal peptide; complexed with envelope glycoprotein I to form an Fc-receptor; involved in cell-to-cell spread
    Names
    envelope glycoprotein E
    YP_009137143.1
    • gE family

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001806.2 Reference assembly

      Range
      141143..143697
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. YP_009137143.1 envelope glycoprotein E [Human herpesvirus 1]

      See identical proteins and their annotated locations for YP_009137143.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P04488
      UniProtKB/TrEMBL
      D3YPM6, Q703C1, Q703C2, Q703C7, Q703C8, Q703C9, Q703E0, Q703E1, Q703E2, Q703E9
      Conserved Domains (1) summary
      PHA03282
      Location:1550
      PHA03282; envelope glycoprotein E; Provisional
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