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    MIR128-1 microRNA 128-1 [ Homo sapiens (human) ]

    Gene ID: 406915, updated on 2-Apr-2017
    Official Symbol
    MIR128-1provided by HGNC
    Official Full Name
    microRNA 128-1provided by HGNC
    Primary source
    See related
    Ensembl:ENSG00000207654 MIM:611774; miRBase:MI0000447
    Gene type
    RNA type
    RefSeq status
    Homo sapiens
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MIR128A; MIRN128A; MIRN128-1; mir-128-1
    microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
    Exon count:
    Annotation release Status Assembly Chr Location
    108 current GRCh38.p7 (GCF_000001405.33) 2 NC_000002.12 (135665397..135665478)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (136422967..136423048)

    Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene zinc finger RANBP2-type containing 3 Neighboring gene G3BP stress granule assembly factor 1 pseudogene Neighboring gene R3H domain containing 1 Neighboring gene RNA, U6 small nuclear 512, pseudogene Neighboring gene uncharacterized LOC107985946 Neighboring gene UBX domain protein 4 Neighboring gene uncharacterized LOC100507600 Neighboring gene lactase

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.


    1. NR_029672.1 RNA Sequence

      Status: PROVISIONAL

      Source sequence(s)

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 108 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p7 Primary Assembly


    1. NC_000002.12 Reference GRCh38.p7 Primary Assembly

      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate CHM1_1.1


    1. NC_018913.2 Alternate CHM1_1.1

      GenBank, FASTA, Sequence Viewer (Graphics)
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