Format

Send to:

Choose Destination

Links from PubMed

    • Showing Current items.

    Enah enabled homolog (Drosophila) [ Mus musculus (house mouse) ]

    Gene ID: 13800, updated on 9-Jul-2017
    Official Symbol
    Enahprovided by MGI
    Official Full Name
    enabled homolog (Drosophila)provided by MGI
    Primary source
    MGI:MGI:108360
    See related
    Ensembl:ENSMUSG00000022995 Vega:OTTMUSG00000050713
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mena; WBP8; Ndpp1; NDPP-1
    Orthologs
    Location:
    1 H5; 1 84.93 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (181896384..182019980, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (183834576..183950111, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene lamin B receptor Neighboring gene predicted gene, 33669 Neighboring gene predicted gene, 38648 Neighboring gene nuclear encoded tRNA serine 1 (anticodon GCT)

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    SH3 domain binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    WW domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    profilin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    actin cytoskeleton organization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    actin filament organization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    actin polymerization or depolymerization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    axon guidance IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    cellular response to leukemia inhibitory factor IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    movement of cell or subcellular component IDA
    Inferred from Direct Assay
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    nervous system development IEA
    Inferred from Electronic Annotation
    more info
     
    neural tube closure IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    actin cytoskeleton TAS
    Traceable Author Statement
    more info
    PubMed 
    cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    filopodium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    focal adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    focal adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    lamellipodium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    stress fiber IDA
    Inferred from Direct Assay
    more info
    PubMed 
    synapse IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    protein enabled homolog
    Names
    NPC derived proline rich protein 1

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083120.2NP_001076589.1  protein enabled homolog isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded protein (isoform 3) is shorter than isoform 1.
      Source sequence(s)
      AC122204, AC165229
      Consensus CDS
      CCDS48473.1
      UniProtKB/TrEMBL
      A0A0A6YW06
      Related
      ENSMUSP00000141344.1, OTTMUSP00000069140, ENSMUST00000195059.5, OTTMUST00000128550
      Conserved Domains (2) summary
      cd01207
      Location:5112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:748781
      VASP_tetra; VASP tetramerization domain
    2. NM_001083121.2NP_001076590.1  protein enabled homolog isoform 4

      See identical proteins and their annotated locations for NP_001076590.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an alternate in-frame exon in the 5' coding region and uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The encoded protein (isoform 4) is shorter than isoform 1.
      Source sequence(s)
      AC122204, AC165229
      Consensus CDS
      CCDS78764.1
      UniProtKB/Swiss-Prot
      Q03173
      Related
      ENSMUSP00000141462.1, OTTMUSP00000069136, ENSMUST00000193703.5, OTTMUST00000128544
      Conserved Domains (2) summary
      cd01207
      Location:5112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:504537
      VASP_tetra; VASP tetramerization domain
    3. NM_008680.3NP_032706.2  protein enabled homolog isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon and contains an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded protein (isoform 2) is shorter than isoform 1.
      Source sequence(s)
      AC122204, AC165229
      Consensus CDS
      CCDS48474.1
      UniProtKB/TrEMBL
      E9QKQ9
      Related
      ENSMUSP00000106659.3, OTTMUSP00000069141, ENSMUST00000111030.5, OTTMUST00000128551
      Conserved Domains (2) summary
      cd01207
      Location:5112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:752785
      VASP_tetra; VASP tetramerization domain
    4. NM_010135.3NP_034265.2  protein enabled homolog isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC122204, AC165229
      Consensus CDS
      CCDS35811.1
      UniProtKB/TrEMBL
      E9QLZ9
      Related
      ENSMUSP00000077781.6, OTTMUSP00000069139, ENSMUST00000078719.12, OTTMUST00000128549
      Conserved Domains (2) summary
      cd01207
      Location:5112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:767800
      VASP_tetra; VASP tetramerization domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      181896384..182019980 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496643.3XP_006496706.1  protein enabled homolog isoform X1

      Conserved Domains (2) summary
      cd01207
      Location:36143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:798831
      VASP_tetra; VASP tetramerization domain
    2. XM_006496645.3XP_006496708.1  protein enabled homolog isoform X3

      Conserved Domains (2) summary
      cd01207
      Location:36143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:783816
      VASP_tetra; VASP tetramerization domain
    3. XM_006496646.3XP_006496709.1  protein enabled homolog isoform X4

      Conserved Domains (2) summary
      cd01207
      Location:36143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:779812
      VASP_tetra; VASP tetramerization domain
    4. XM_006496652.3XP_006496715.1  protein enabled homolog isoform X10

      Related
      ENSMUSP00000141936.1, OTTMUSP00000069138, ENSMUST00000193074.5, OTTMUST00000128548
      Conserved Domains (2) summary
      cd01207
      Location:36143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:498531
      VASP_tetra; VASP tetramerization domain
    5. XM_006496650.3XP_006496713.1  protein enabled homolog isoform X8

      Related
      ENSMUSP00000106653.4, OTTMUSP00000069137, ENSMUST00000111024.9, OTTMUST00000128545
      Conserved Domains (2) summary
      cd01207
      Location:36143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:556589
      VASP_tetra; VASP tetramerization domain
    6. XM_006496651.3XP_006496714.1  protein enabled homolog isoform X9

      Conserved Domains (2) summary
      cd01207
      Location:36143
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:535568
      VASP_tetra; VASP tetramerization domain
    7. XM_006496649.3XP_006496712.1  protein enabled homolog isoform X7

      Conserved Domains (1) summary
      pfam08776
      Location:694727
      VASP_tetra; VASP tetramerization domain
    8. XM_006496648.3XP_006496711.1  protein enabled homolog isoform X6

      Conserved Domains (1) summary
      pfam08776
      Location:698731
      VASP_tetra; VASP tetramerization domain
    9. XM_006496647.3XP_006496710.1  protein enabled homolog isoform X5

      Related
      ENSMUSP00000136863.1, ENSMUST00000177811.7
      Conserved Domains (2) summary
      cd01207
      Location:5112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:769802
      VASP_tetra; VASP tetramerization domain
    10. XM_006496644.3XP_006496707.1  protein enabled homolog isoform X2

      Conserved Domains (2) summary
      cd01207
      Location:5112
      EVH1_Ena_VASP-like; Enabled/VASP family EVH1 domain
      pfam08776
      Location:792825
      VASP_tetra; VASP tetramerization domain

    RNA

    1. XR_001780490.1 RNA Sequence

    Support Center