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    greA transcript cleavage factor [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947696, updated on 19-Nov-2016
    Gene symbol
    greA
    Gene description
    transcript cleavage factor
    Primary source
    EcoGene:EG10415
    Locus tag
    b3181
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3170; JW3148
    Summary
    HT_Cmplx24_Cyt: [More information is available at EcoGene: EG10415]. GreA stimulates the mRNA cleavage activity of RNA polymerase , which acts to release a polymerase complex that has stalled or incorporated an incorrect nucleotide . [More information is available at EcoCyc: EG10415].
    Sequence:
    NC_000913.3 (3328239..3328715, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene 23S rRNA U2552 2'-O-ribose methyltransferase, SAM-dependent Neighboring gene RNA binding protein associated with pre-50S ribosomal subunits Neighboring gene D-alanyl-D-alanine carboxypeptidase Neighboring gene GTPase involved in cell partioning and DNA repair

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Gene Ontology Provided by GO

    Function Evidence Code Pubs
    bacterial-type RNA polymerase holo enzyme binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA-templated transcription, elongation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of DNA-templated transcription, elongation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Names
    transcript cleavage factor
    NP_417648.4
    • transcription elongation factor: cleaves 3' nucleotide of paused mRNA

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3328239..3328715 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417648.4 transcript cleavage factor [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417648.4

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P0A6W5
      Conserved Domains (3) summary
      PRK00226
      Location:1157
      greA; transcription elongation factor GreA; Reviewed
      pfam01272
      Location:83157
      GreA_GreB; Transcription elongation factor, GreA/GreB, C-term
      pfam03449
      Location:474
      GreA_GreB_N; Transcription elongation factor, N-terminal
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